background: the protein of niemann-pick type c1 (npc1) gene promotes the egress of cholesterol from late endosomes and lysosomes to other cellular compartments and contributes to a process known as reverse cholesterol transport. this study aimed to examine whether promoter methylation of npc1 is associated with risk of cardiovascular disease (cvd). methods: fifty cvd patients and 50 healthy sub...

background nonalcoholic fatty liver disease (nafld) is one of the most common reasons of enzyme increase in liver. in about 10 percent of patients with nafld, the disease progresses toward non alcoholic steatohepatitis (nash) and about one third of them may progress toward cirrhosis, liver dysfunction, and even hepatocellular carcinoma. objectives according to high prevalence of nafld and the f...

background: this study was performed to evaluate periodontal status in patients with cardiovascular disease (cvd) and assessment of periodontal diseases prevalence in these patients. materials and methods: in this cross-sectional study, data on 100 patients were collected with mean age of 51 ± 11 years. the case group included of 50 patients with confirmed cvd who referred to ali-ibn abi talib ...

introduction: the aim of this study was to evaluate the effects of aerobic exercise on brain natriuretic peptide (bnp) and c-reactive protein (crp) levels in women with cardiovascular diseases. materials and methods: in this semi experimental study, thirty female patients with at least one coronary artery stenosis (more than70%) were chosen and divided into two groups of aerobic training (n=15)...

conclusions the identification of the beneficial cardiovascular effects of dhea (s) and a better understanding of the involved mechanisms should be helpful to develop new strategies or pharmacologic approaches for many lethal diseases in western countries. context dehydroepiandrosterone (dhea) and its sulfate ester, dehydroepiandrosterone sulfate (dhea-s) have been considered as putative anti-a...

since the report from the national high blood pressure (bp) education program working group on bp in children and adolescents and the introduction of a new description called prehypertension many data have been provided on its rate of progression to hypertension, its prevalence and association with other cardiovascular (cv) risk factors and its therapy. making a diagnosis of prehypertension in ...

purpose sudden death of a competitive athlete is a tragedy that is usually caused by a previously unsuspected cardiovascular disease. the aim of this study was to clarify the role of noninvasive testing in pre-participation cardiovascular evaluation of elderly wrestlers. methods we included 63 iranian elderly wrestlers who participated in tehran international elderly wrestlers’ preparation camp...

recently, cell therapy has sparked a revolution in ischemic heart disease that will in the future help clinicians to cure patients. earlier investigations in animal models and clinical trials have suggested that positive paracrine effects such as neoangiogenesis and anti-apoptotic can improve myocardial function. in this regard the royan cell therapy center designed a few trials in collaboratio...

psychological problems play a critical role in development of cardiovascular disease. several mechanisms were suggested to explain the association and mechanism of this effect, recently. knowledge of the mechanisms mediating the association between psychological status and heart disease could help in developing treatments. the effects of mind and mood on the cardiovascular system can be due to ...