Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in bone contact as its chemical composition is similar to that of bone material. Porous HA ceramics have found enormous use in biomedical applications including bone tissue regeneration, cell proliferation, and drug delivery. In bone tissue engineering it has been applied as filling material for bone defec...

A porous poly(L-lactic acid)/β-tricalcium phosphate (PLLA/β-TCP) composite scaffold was fabricated using a novel technique comprising powder mixing, compression molding, low-temperature treatment, and particulate leaching without any organic solvent. The effect of this scaffold on osteoblast proliferation and differentiation was evaluated in vitro. The fabricated scaffold had a homogeneously in...

Introduction Scaffolds fabricated from silk have shown good osteoinduction. However, the mechanical properties were insufficient to match native bone. We previously investigated the effects of mineral incorporation (by coating as well as embedding into the silk phase) as a method to enhance mechanical properties of porous silk scaffolds for bone tissue engineering. Based on encouraging results ...

Three-dimensional (3-D) scaffolds with intrinsic porous structures are desirable in various tissue regeneration applications. In this study, a unique method that combines thermally induced phase separation with a photocrosslinking process was developed for the fabrication of 3-D crosslinked polymer scaffolds with densely interconnected porous structures. Biodegradable poly(propylene fumarate)-c...

In this paper, the acoustical treatment of double-panel structures lined with poroelatic materials is predicted using analytical method in order to study the effective usage of the various boundary conditions of porous layer and to identify the effective parameters on the transmission loss of the multilayer systems. Therefore, inertia and viscous coupling along with thermal and elastic coupling...

Biodegradable porous biomaterial scaffolds play a critical role in bone regeneration. In this study, the porous nano-hydroxyapatite/collagen/poly(lactic-co-glycolic acid)/graphene oxide (nHAC/PLGA/GO) composite scaffolds containing different amount of GO were fabricated by freeze-drying method. The results show that the synthesized scaffolds possess a three-dimensional porous structure. GO slig...

A series of column experiments were performed using different bacterial inoculation scenarios to maximize the TCE-degrading potential of a multi-species biofilm. The single-species population dynamics of Burkholderia cepacia PR1 pTOM31c, a TCE-degrading microorganism unable to form a significant biofilm, were examined and compared to those of a dual-species population containing both B. cepacia...

Tightly bonding of bioactive coating is the first crucial need for orthopaedic implants. This study describes a novel and convenient technique to prepare bioactive coating with high adhesion on orthopaedic substitutes made of polymeric matrix. Here, a chemical corrosion method has been adopted to fabricate a coating on the surface of injection-moulded polyamide66 (PA66) substrates by corrosive ...

This study presents the manufacture of highly porous hydroxyapatite by a novel technique that employs the foaming of suspensions prior to the in situ polymerization of organic monomers contained in the compositions. This method produces strong gelled bodies with up to 90% porosity that can withstand machining in the green state. Complex-shaped components can be obtained if the process comprises...

Two models for predicting the stress-strain curve of porous NiTi under compressive loading are presented in this paper. Porous NiTi shape memory alloy is considered as a composite composed of solid NiTi as matrix and pores as inclusions. Eshelby’s equivalent inclusion method and Mori-Tanaka’s mean-field theory are employed in both models. Two types of pore connectivity are investigated. One is ...