The sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) actively transports into the sarcoplasmic to facilitate cardiac muscle relaxation. Phospholamban (PLN) allosterically inhibits SERCA, and an imbalance of SERCA2a, dominant isoform, PLN content disrupts homeostasis contractility. A previous study has shown that ovariectomized (OVX) rats have reduced SERCA activity due lowered SERCA2a increased...

Sign language recognition has spawned more and more interest in human–computer interaction society. The major challenge that SLR recognition faces now is developing methods that will scale well with increasing vocabulary size with a limited set of training data for the signer independent application. The automatic SLR based on hidden Markov models (HMMs) is very sensitive to gesture's shape inf...

This paper presents a scheme for separately characterizing computational algorithms and characterizing computing hardware, and then combining those analyses to find the suitability of a piece of hardware for a scientific algorithm. The analysis of the algorithm concentrates on a continuous computational density function, ρ, that characterizes the loss of efficiency of computation as a function ...