The physiology of climbing fiber signals in cerebellar Purkinje cells has been studied since the early days of electrophysiology. Both the climbing fiber-evoked complex spike and the role of climbing fiber activity in the induction of long-term depression (LTD) at parallel fiber-Purkinje cell synapses have become hallmark features of cerebellar physiology. However, the key role of climbing fibe...

Article history: Received: 22 May 2013 Accepted: 19 June 2013 Available online: 21 Jan 2015 ZJRMS 2015 Feb; 17(2): 60-62 Background: Opioid receptors change in CNS by anti thyroid hormones drugs. In this study effect of acute and chronic methimazole (aMTZ and cMTZ) administration on morphine withdrawal were investigated. Materials and Methods: In this experimental study adult male mice divided ...

Aiming at the functional requirement of climbing up the stairs, the dynamics and stability during a tracked mobile robot’s climbing of stairs is studied. First, from the analysis of its cross‐country performance, the mechanical structure of the tracked mobile robot is designed and the hardware composition of its control system is given. Second, based on the anal...

Cerebellar climbing fiber activity encodes performance errors during many motor learning tasks, but the role of these error signals in learning has been controversial. We compared two motor learning paradigms that elicited equally robust putative error signals in the same climbing fibers: learned increases and decreases in the gain of the vestibulo-ocular reflex (VOR). During VOR-increase train...

BACKGROUND Climbing is a physical activity and sport involving many subdisciplines. Minimization of prolonged pauses, use of a relatively simple path through a route and smooth transitions between movements broadly define skilled coordination in climbing. OBJECTIVES To provide an overview of the constraints on skilled coordination in climbing and to explore future directions in this emerging ...