Investigating regulation and function of the Hox genes, key regulators of positional identity in the embryo, opened a new vista in developmental biology. One of their most striking features is collinearity: the temporal and spatial orders of expression of these clustered genes each match their 3' to 5' order on the chromosome. Despite recent progress, the mechanisms underlying collinearity are ...

Hox gene collinearity (HGC) is a multi-scalar property of many animal phyla particularly important in embryogenesis. It relates entities and events occurring clusters inside the chromosome DNA embryonic tissues. These two differ linear size by more than four orders magnitude. HGC observed as spatial (SC), where genes are located order (Hox1, Hox2, Hox3 …) along 3′ to 5′ direction genome corresp...

Collinearity and near-collinearity of predictors cause difficulties when doing regression. In these cases, variable selection becomes untenable because of mathematical issues concerning the existence and numerical stability of the regression coefficients, and interpretation of the coefficients is ambiguous because gradients are not defined. Using a differential geometric interpretation, in whic...

The vertebrate A-P axis is a time axis. The head is made first and more and more posterior levels are made at later and later stages. This is different to the situation in most other animals, for example, in Drosophila. Central to this timing is Hox temporal collinearity (see below). This occurs rarely in the animal kingdom but is characteristic of vertebrates and is used to generate the primar...

in mulberry (morus sp.), grown for its foliage, which is the sole food for the silkworm (bombyx mori l.), evolving high yielding varieties is a long drawn and laborious process. one of the important selection parameter that has significant positive correlation with leaf yield is total shoot length [tsl] of the mulberry plant. measuring the length of all the shoots of the test genotypes to get t...