cancer starts with a change in one single cell. this change may be initiated by external agents and genetic factors. cancer is a leading cause of death worldwide and accounts for 7.6 million deaths (around 13% of all deaths) in 2008. lung, stomach, liver, colon and breast cancer cause the most cancer deaths each year. in this review, different aspects of gastric cancer; including clinical, path...

Dear Editors: Adenocarcinoma of colon and rectum is the second most common cancer of the gastrointestinal (GI) tract in children. The development of carcinoma of colon in general appears to be associated with several predisposing factors such as familial polyposis, hereditary non-polyposis syndromes, ulcerative colitis, previous ureterosigmoidostomy or radiation therapy and dietary factors (hig...

Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder of the small intestine colon. IBD includes ulcerative colitis (UC) Crohn’s (CD), it main reason for expansion colon cancer, referred to as colitis-associated cancer (CAC). Oral colon-targeted microsphere based drug delivery system containing sulfasalazine was prepared, optimized characterized. The micros...

background: colorectal cancer (crc) is the third common malignancy all over the world. modern life styles affecting nutritional habits have been providing a potential impact on crc. this study aims to assess the nutritional characteristics in crc patients of golestan province, northeast of iran. methods: all incident crc cases (n=47) in northeast of iran (2004-2005) and a matched number of heal...

Soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. However, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. Therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 MAPK) as the main therapeutic targets...

Introduction: We report a case of a 64-year old man with a history of colon carcinoma. He underwent fine-needle aspiration by CytoFoam-core and diagnosis of metastatic colon cancer to the thyroid gland. Case presentation: In this case report, a solid thyroid nodule in the right lobe of a 64-year-old male was aspirated. The cytological smears showed a small group of atypical cells with the obvi...

Background: Common cancers such as colon, breast, and lung cancer are increasing in developing countries. Objective: This study was conducted to determine 10-year trends and changes in common cancers in patients from a referral hospital in Tehran, Iran. Methods: This cross-sectional study investigated a study population comprising colon, stom...

Introduction: We report a case of a 64-year old man with a history of colon carcinoma. He underwent fine-needle aspiration by CytoFoam-core and diagnosis of metastatic colon cancer to the thyroid gland. Case presentation: In this case report, a solid thyroid nodule in the right lobe of a 64-year-old male was aspirated. The cytological smears showed a small group of atypical cells with the obvi...

background: acute obstruction of the colon continues to be a lethal disease with little improvement in the mortality rate over the past 50 years. so, this study was undertaken to define the causes of colon obstruction and their probable changes after years. â  methods: from 1979 to 2004, all records of patients with definite diagnosis of intestinal obstruction at all hospitals affiliated to shi...

soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. however, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 mapk) as the main therapeutic targets were...