OBJECTIVE The aim of this article was to review published research articles on leptospirosis, in particular the recent incidence of leptospirosis in Malaysia and the currently available diagnostic methods for the detection of leptospirosis. METHODS PubMed, Google Scholar and Google Search databases were searched using the key words Leptospira and leptospirosis. A total of seventy-six referenc...

Leptospirosis is a zoonotic disease with global distribution that caused by pathogenic spirochetes of the genus Leptospira. Accurate diagnosis for differentiation of leptospirosis from other pyrogenic infections prevailing in the same locality and is imperative for proper treatment. Therefore a molecular diagnostic test with high specificity and sensitivity such as PCR is essential. Gene encodi...

BACKGROUND The relationship between inducible nitric oxide synthatase activity and disease severity in leptospirosis is unclear. Nitric oxide is converted to nitrites and nitrates, thus nitrite and nitrate levels (NOx) in serum are considered surrogate markers for nitric oxide. NOx are excreted through the kidneys, and elimination is diminished in renal impairment. We assessed the correlation o...

Leptospirosis is a zoonosis caused by pathogenic bacteria of the genus Leptospira. This disease affects several animals and humans. Symptoms leptospirosis can range from mild to severe, may in some cases lead death. For diagnosis leptospirosis, microscopic agglutination test considered “gold standard”; however, it has limitations studies are being conducted develop alternative methods screening...

BACKGROUND Leptospirosis is relatively uncommon in children. Following torrential rains and flooding an outbreak of leptospirosis was suspected in Mumbai. AIMS To investigate the possibility of an outbreak of leptospirosis and describe the clinical illness. METHODS From 24 July to 14 September 2000, children with a history of abrupt onset of high fever (>39 degrees C), who presented to our ...

background: leptospirosis is a zoonotic disease that is recognized as a re-emerging global public health issue, especially in tropical and subtropical countries. malaysia, for example, has increasingly registered leptospirosis cases, outbreaks, and fatalities over the past decade. one of the major industries in the country is the palm oil sector, which employs numerous agricultural workers. the...

INTRODUCTION The incidence of canine leptospirosis in Brazil needs to be assessed. METHODS The same dogs in southern Brazil were sampled over two years to determine the prevalence, incidence and association of canine leptospirosis with various risk factors. RESULTS In 2009, the prevalence was 33 (14.4%) of 228 dogs, with a predominance of serovar Canicola (33.4%). In 2010, 90 dogs were re-e...

BACKGROUND Leptospirosis, a disease caused by Leptospira species, a spirochaete bacterium that can develop in an appropriate environment and/or grow in human and/or animal hosts, is a serious problem for the Ministry of Public Health, Thailand. OBJECTIVE To investigate people's perceptions and behavioral risks regarding leptospirosis infection. METHODS The cross-sectional descriptive study ...

Leptospirosis is a zoonotic disease caused by spirochetes of the genus Leptospira. 1,2 Leptospirosis affects human beings and many other species of vertebrates, it can present in a wild spectrum of clinical manifestations in human being. 3 Many wild and domestic animals are reservoirs for leptospira organisms and they shed these organisms in their urine thereby contaminating fresh water, mud an...