[figure: see text] A conceptually new palladium-catalyzed amidation reaction is described for the synthesis of beta-amido ketones based on derailing the Wacker oxidation of enones. This reaction generates a new carbon-nitrogen bond via a palladium-catalyzed conjugate addition of a carbamate nucleophile to an enone. The regiocontrol, mild and neutral conditions, lack of preactivation of the nucl...

A buffer is defined as a compound that in small concentrations can impart a resistance to large pH changes. Common buffers contain two substances, a conjugate base and a conjugate acid. There are acidic buffers that contain a weak acid and the salt of a weak acid (the conjugate base) and basic buffers that contain a weak base and the salt of a weak base (the conjugate acid). The combination of ...

The temperature and pressure dependence of the addition reaction of ethyl methyl ketone (EMK) with HȮ2 radical has been calculated using the master equation method employing conventional transition state theory estimates for the microcanonical rate coefficients in the temperature range of 600–1600 K. Geometries, frequencies, and hindrance potentials were obtained at the B3LYP/6-311G(d,p) level ...

ELISA data is usually handled in the MS Excel worksheets through different methods and different formulas. Accurate and precise calculations of the data is time consuming and tedious. ELISA Analyzer was developed with a user friendly interface to streamline titration and analysis of the data obtained from ELISA and improve rapid and lucid presentation of the results. The software can also hel...

This study aims to determine of Chloramphenicol test for Vannamei shrimp conducted ELISA (Enzyme-Linked Immunosorbent Assay) method with 1 treatment. is done by adding the Abenzyme conjugate, and ends addition substrate reaction stop buffer. Each treatment was performed three times. The value (CAP) (Litopenaeus vannamei) which tested at 4 weeks ranged from 0.021 0.153 ppb. result showed in stil...

elisa data is usually handled in the ms excel worksheets through different methods and different formulas. accurate and precise calculations of the data is time consuming and tedious. elisa analyzer was developed with a user friendly interface to streamline titration and analysis of the data obtained from elisa and improve rapid and lucid presentation of the results. the software can also help ...

A wide variety of chiral succinimides have been prepared in high yields and enantioselectivities by an asymmetric conjugate addition of 1,3-dicarbonyl compounds to maleimides under very mild reaction conditions using the bifunctional benzimidazole-derived organocatalyst 5f. Computational and NMR studies support the hydrogen-bonding activation role of the catalyst and the origin of the stereosel...