UV radiation-induced immunosuppression has been implicated in the development of skin cancers. Green tea polyphenols (GTP) in drinking water prevent photocarcinogenesis in the skin of mice. We studied whether GTPs in drinking water (0.1-0.5%, w/v) prevent UV-induced immunosuppression and (if so) potential mechanisms of this effect in mice. GTPs (0.2% and 0.5%, w/v) reduced UV-induced suppressio...

Sensitization through UV-exposed skin induces regulatory T cells (Treg). In contrast to the classical CD4+CD25+ Treg that act contact dependent, UV-induced Treg (UV-Treg) suppress via IL-10, indicating a distinct subtype that requires further characterization. Depletion studies revealed that UV-Treg express the glucocorticoid-induced TNF family-related receptor (GITR) and the surface molecule n...

The nonlinear system becomes an area with numerous investigations over the past decades. The conventional modal analysis could not be  applied on nonlinear continuous system which makes it impossible to construct the reduced order models and obtain system response based on limited number of measurement points. Nonlinear normal modes provide a useful tool for extending modal analysis to nonlinea...

UV crosslinking is an appropriate method to identify proteins that directly contact nucleic acid, e.g., RNA. In combination with modern mass spectrometric (MS) analysis such an approach provides the opportunity to reveal not only the nature of the crosslinked proteins but also to identify the actual crosslinking sites between the protein and the nucleic acid. However, the relatively low yield i...

The elimination of mercury, low energy consumption, and heat make the ultraviolet light-emitting diode (UV-LED) system emerge as a promising alternative to conventional UV-mercury radiation coating. Hence, series hydrophobic coatings based on urethane acrylate oligomer fluorinated monomer via UV-LED photopolymerisation was designed in this paper. presence fluorine component at 1160 cm−1, 1235 1...

INTRODUCTION Penicillin G (PG) is used in a variety of infectious diseases, extensively. Generally, when antibiotics are introduced into the food chain, they pose a threat to the environment and can risk health outcomes. The aim of the present study was the removal of Penicillin G from an aqueous solution through an integrated system of UV/ZnO and UV/WO3 with Ultrasound pretreatment. METHODS ...

In this paper, an innovative method to create embedded microchannels is presented. The presented technology is based on a direct-write technique using a scanning laser system to pattern a single layered SU-8. The enormous flexibility of the scanning laser system can be seen in two key features: the laser pulsing can be controlled spot-by-spot with variable exposure doses, and the laser intensit...

High-throughput fabrication of graphically encoded hydrogel microparticles is achieved by combining flow contact lithography in a multichannel microfluidic device and a high capacity 25 mm LED UV source. Production rates of chemically homogeneous particles are improved by two orders of magnitude. Additionally, the custom-built contact lithography instrument provides an affordable solution for p...