There is growing evidence that stressors occurring during pregnancy can impair biological and behavioral adaptation to stress in the adult offspring. Mechanisms by which stress in the pregnant rat can influence development of the offspring are still unknown. In the present study, we investigated the involvement of maternal corticosterone secretion during pregnancy on the hypothalamo-pituitary-a...

We used captive European starlings (Sturnus vulgaris) to test whether corticosterone responses differed in birds held under normal laboratory conditions or conditions of chronic stress. Surprisingly, both basal corticosterone concentrations and corticosterone responses to acute stress were significantly reduced when birds were chronically stressed. To determine the mechanism underlying this red...

ABE, K. AND HIROSE, T. Effect of Corticosterone and Cortisol on Corti costeroidogenesis in Isolated Rat Adrenal Cells. Tohoku J . exp. Med., 1974, 112 (2), 195-196 Isolated rat adrenal cells were incubated with corticosterone or cortisol in the presence of ACTH. When the corticosterone production in the absence of exogenous corticoids was taken as 100%, it was decreased to 77•}3 and 62•}4% by t...

Observations suggest that corticosterone, the principal glucocorticoid hormone in the rat, can modulate the behavioral effects of drugs of abuse. In this report, the influence of corticosterone on intravenous self-administration of cocaine was studied. In the first experiment, cocaine intravenous self-administration in adrenalectomized rats and in adrenalectomized rats receiving corticosterone ...

In vertebrates, baseline glucocorticoid concentrations vary predictably on a diel basis, usually peaking shortly before the onset of activity. Presumably, circadian patterns in glucocorticoid secretion have evolved to match predictable rises in energetic need. In mice from lines selectively bred for high voluntary wheel-running, previous studies have reported that baseline plasma corticosterone...

Corticosterone has been demonstrated in human adrenal perfusates (l), and in adrenal venous blood obtained by cannulation of the adrenal vein immediately prior to adrenalectomy (2). Several investigators (Morris and Williams (3), Bush and Sandberg (4), Weichselbaum and Margraf (5), and Sweat (1)) have reported the presence of corticosterone or “corticosterone-like” substances in the peripheral ...

Synopsis Artificial light at night (hereafter “ALAN”) affects 88% of the land area in Europe and almost half USA, with even rural areas exposed to lights from agricultural industrial buildings. To date, there have been few studies that assess impacts ALAN on both wildlife behavior physiology. However, may alter energy expenditure and/or stress physiology during breeding period, potentially redu...

Augmented cardiovascular responses to acute stress can predict cardiovascular disease in humans. Chronic systemic increases in glucocorticoids produce enhanced cardiovascular responses to psychological stress; however, the site of action is unknown. Recent evidence indicates that glucocorticoids can act within the dorsal hindbrain to modulate cardiovascular function. Therefore, we tested the hy...

Previous studies in rat have demonstrated decreased number of mitochondria and uncoupling of oxidative phosphorylation after administration of glucocorticoids but at supraphysiological doses and using synthetic glucocorticoids. To analyze the relationships between corticosterone levels (the natural glucocorticoid in rat) and muscle mitochondrial metabolism, Lewis and Fischer 344 rats were bilat...