Although cataract surgery is considered a safe procedure, post-surgery complications such as endophthalmitis and ocular inflammation, may occur. To prevent this, antibiotics anti-inflammatories are prescribed in the form of eye drops during post-operatory period, but they lead to low drug bioavailability target tissues. The objective this work develop an intraocular lens (IOL) material deliver ...

Abstract The role of natural fractures in future reservoir performance is prominent. fractured porous media composed an interconnected network and blocks the medium where occur various scales have a strong influence either when most flow concentrated them or they act as barriers. A general numerical model for discrete fracture networks (DFN) usually employed to handle observed wide variety prop...

Generation of naturally fractured reservoir subsurface fracture maps and prediction its production potential are considered complex process due to insufficient data available such as bore hole images, core data and proper reservoir simulator model. To overcome such shortcomings, the industry has relied on geo-statistical analyses of hard and soft data, which are often referred to as static data...

Constant head tests are commonly used for field measurements of fracture transmissivity. As a bulk transmissivity is measured each test section, it frequently unclear how this relates to the hydraulic properties individual fractures. The goal study determine if constant conducted at scales larger than average spacing can be generate discrete network (DFN) models that describe transport. methodo...

We consider flows in fractured media, described by Discrete Fracture Network (DFN) models. We perform an Uncertainty Quantification analysis, assuming the fractures’ transmissivity coefficients to be random variables. Two probability distributions (log-uniform and log-normal) are used within different laws that express the coefficients in terms of a family of independent stochastic variables; t...

The magnetic navigation of drugs in the vascular network promises to increase the efficacy and reduce the secondary toxicity of cancer treatments by targeting tumors directly. Recently, dipole field navigation (DFN) was proposed as the first method achieving both high field and high navigation gradient strengths for whole-body interventions in deep tissues. This is achieved by introducing large...