BACKGROUND Considerable studies directly connect the complications in diabetic patients, and especially peripheral neuropathy, with the emergence of depression. Neuropathetic pain may deteriorate the general health status of the diabetic patient and glycaemic regulation. PURPOSE The purpose of this study was to investigate the appearance and degree of diabetic peripheral neuropathy and its co...

The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the most common and incapacitating symptoms of diabetic neuropathy and its pharmacological control is complex. The effectiveness of antidepressive agents has been described in different types of neuropathic pain, but their effectiveness, when used as analgesics in painfu...

Background: Autonomic Diabetic Neuropathy, the most frequent diabetic consequence, is commonly treated with medicines without success. Diabetes a chronic disease due to insulin resistance or reduced secretion, India known as "diabetic world capital," projected growth of 63 %, exceeding 98 million by 2030. The latest diabetes mellitus statistics are worrying, stating that around 150 individuals ...

PURPOSE Assessment of quality of life, especially from the psychological point of view, is likely to be strongly influenced by the degree of acceptance of one's own illness and the resultant negative emotional reactions associated with the illness itself. The aim of the present study was to determine the relationship between quality of life and the degree of acceptance of illness in diabetic pa...

the aim of the present study was to investigate the effect of endurance training on syd gene expression in motor neurons of rats with diabetic neuropathy. 12 wistar male rats were randomly assigned to 3 groups (each group 4 subjects): diabetic trained (dt), diabetic untrained (dc) and healthy control (hc). two weeks after stz injection to induce diabetes, diabetic neuropathy was demonstrated by...

Diabetic neuropathy is a major complication of diabetes mellitus affecting to an equal extent type 1 and type 2 patients. Various mechanisms including metabolic and vascular abnormalities have been proposed to explain the progressive pathological changes that occur in peripheral nerve. Regardless of the precise mechanisms, structural abnormalities lead to functional changes which eventually res...

PURPOSE We previously reported that insulin resistance, low high-density lipoprotein (HDL) cholesterol, and glycaemic exposure Index are independently associated with peripheral neuropathy in Korean patients with type 2 diabetes mellitus. We followed the patients who participated in that study in 2006 for another 6 years to determine the relationship between insulin resistance and neuropathy. ...