OBJECTIVE Thymoquinone (TQ), as the main component of Nigella Sativa plant, shows anticancer properties. This study was aimed to evaluate the combined effect of TQ and Tamoxifen (TAM) on viability and apoptosis of human breast cancer cell lines. MATERIALS AND METHODS In this experimental study, estrogen positive MCF-7 and estrogen negative MDA-MB-231 human breast cancer cell lines were induce...

BACKGROUND AND AIMS Glacier foreland plants are highly threatened by global warming. Regeneration from seeds on deglaciated terrain will be crucial for successful migration and survival of these species, and hence a better understanding of the impacts of climate change on seedling recruitment is urgently needed to predict future plant persistence in these environments. This study presents the f...

Recent studies have documented a relationship between increased morbidity and mortality from cardiovascular diseases and a history of weight cycling (WC) in obese subjects. We performed a cross-sectional analysis in 96 weight-cycling android obese women, matched with 96 non-weight-cycling android obese women by age, body mass index (BMI) and waist-to-hip ratio (WHR), to evaluate any increase in...

HIV increases the likelihood that a person will develop TB. Starting them on anti-retroviral therapy (ART) reduces their risk of TB but not to the level in HIV negative people. Since HIV-positive people who are on ART can expect to live a normal life for several decades this raises the possibility that their elevated risk of infection, lasting for a long time, could lead to an increase in the p...

This study examined how students' interest, self-efficacy, and perceived difficulty change during a task, those changes relate to each other, they predict performance. Sixth-graders (N = 1024) rated their repeatedly dynamic problem-solving task. Results from the estimated non-linear piecewise latent growth curve models showed interest self-efficacy decrease, first increase, then over time. The ...