BACKGROUND Ethanol, a commonly available agent, has been used to successfully ablate cystic and solid lesions in the pancreas. The aim of this study is to investigate the effects of an ethanol injection into the porcine pancreas and observe the time-dependent image changes in the pancreatic parenchyma. METHODS Pure ethanol was injected into the pancreatic tail using a 25-gauge EUS needle with...

In vivo studies in rats demonstrated that acute intragastric administration of ethanol (3 g/kg BW) resulted in a reduced net absorption of fluid and calcium. Thirty minutes after an i.v. injection of 2 microCi 45Ca, the gastrointestinal 45Ca content in ethanol-treated rats was significantly higher than in controls indicating an increase in calcium secretion. The effect of ethanol on calcium mov...

The current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. Among different vehicles, cationic liposomes are frequently used for delivery of genetic material. This investigation aims to prepare and optimize DOTAP cationic liposomes containing an antisense oligonuclotide (AsODN) against protein kinase C alpha in non-small cells lung...

We present an interesting case of profound bronchospasm that we postulate was caused by injection of ethanol during embolization of a left transverse sinus dural fistula. There is excellent documentation in the literature of the development of transient pulmonary hypertension and decreased right-side cardiac output following embolization with this agent; however, there have been only anecdotal ...

AIMS The effects of chronic alcohol consumption (8 weeks) on glucose kinetics, in the absence (water, 4 g/kg) and presence of an acute ethanol dose (4 g/kg), were examined in 48 h fasted male and female Wistar rats. METHODS Primed continuous infusions of [6-3H]- and [U-14C]glucose were employed to assess rates of glucose appearance (Ra), glucose disappearance (Rd), and apparent glucose carbon...

Start of fuel injection and fuel type are two important factors affecting engine performance and exhaust emissions in internal combustion engines. In the present study, a one-dimensional computational fluid dynamics solution with GT-Power software is used to simulate a six-cylinder diesel engine to study the performance and exhaust emissions with different injection timing and alternative fuels...

In the present study, we described an easily reproducable experimental pancreatits model induced by biliopancreatic duct injection of ethyl alcohol. Seventy Wistar albino rats were divided equally into seven groups randomly: the control group (group 1), acute pancreatitis groups; induced by 20% ethanol (group 2), 48% ethanol (group 3), 80% ethanol (group 4), chronic pancreatitis groups; induced...

AIMS Previous studies have shown that CB(1) cannabinoid receptors are involved in the behavioural effects induced by chronic ethanol administration in Wistar rats by using SR 141716, a CB(1) cannabinoid receptor antagonist. These studies have now been extended to investigate the effect of acute and chronic alcoholization on blood ethanol concentration (BEC) and ethanol preference in CB(1) knock...

BACKGROUND AND PURPOSE We evaluated the differences between percutaneous ethanol injection with and without aspiration of ethanol-mixed fluid for treatment of benign cystic thyroid nodules. METHODS We examined 60 patients with benign cystic thyroid nodules confirmed by fine-needle aspiration biopsy and divided them into 2 groups according to nonaspiration (group A, n = 30) or aspiration (grou...

The model developed previously for evaluating the impact of direct ethanol injection on the avoidance of knock in spark ignition engines is used to evaluate the trends of changes in compression ratio and variation in the inlet pressure. The ethanol fraction requirements through the engine map is calculated using detailed chemical kinetics model, and a vehicle simulation is used to determine the...