We introduce a new categorical framework for studying derived functors, and in particular for comparing composites of left and right derived functors. Our central observation is that model categories are the objects of a double category whose vertical and horizontal arrows are left and right Quillen functors, respectively, and that passage to derived functors is functorial at the level of this ...

I will build some standard resolutions for Mackey functors which are projective relative to p-subgroups. Those resolutions are closely related to the poset of p-subgroups. They lead to generalizations of known results on cohomology. They give a way to compute the Cartan matrix for Mackey functors, in terms of p-permutation modules, and to precise the structure of projective Mackey functors. The...

Exercise training (ExT) normalizes the increased sympathetic outflow in heart failure (HF), but the underlying mechanisms are not known. We hypothesized ExT would normalize the augmented activation of the paraventricular nucleus (PVN) via an angiotensinergic mechanism during HF. Four groups of rats used were the following: 1) sham-sedentary (Sed); 2) sham-ExT; 3) HF-Sed, and 4) HF-ExT. HF was i...

Rhetorical biset functors can be defined for any family of finite groups that is closed under subquotients up to isomorphism. The rhetorical p-biset functors almost coincide with the rational p-biset functors. We show that, over a field with characteristic zero, the rhetorical biset functors are semisimple and, furthermore, they admit a character theory involving primitive characters of automor...

Retrieval of consolidated memories induces a labile phase during which memory can be disrupted or updated through a reconsolidation process. A central component of behavioral updating during reconsolidation using a retrieval-extinction manipulation (Ret+Ext) is the synaptic removal of a calcium-permeable-α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor (CP-AMPARs) in the lateral amyg...