Chemosignals play a crucial role in social and sexual communication among inter- and intra-species. Chemical cues are bound with protein that is present in the pheromones irrespective of sex are commonly called as pheromone binding protein (PBP). In rats, the pheromone compounds are bound with low molecular lipocalin protein α2u-globulin (α2u). We reported farnesol is a natural endogenous ligan...

The study involved 30 dogs with otitis complicated by Malassezia pachydermatis . animals were divided into 2 groups: experimental (n = 15) and control 15). group was prescribed veterinary ear drops Surolan + a solution of the drug Farnesol; - Surolan. showed that when Farnesol is added to treatment regimen for fungal etiology in dogs, small changes clinical composition blood are recorded, chara...

Abstract In grape berries ( Vitis vinifera L.), sesquiterpenes are mainly accumulated as hydrocarbons in the epicuticular wax layer of grapes, whereas monoterpenes, which predominantly present alcohols, glycosylated and stored glycosides vacuoles berry cells. this study, extensive analysis hydrolysates by means comprehensive two-dimensional gas chromatography–time-of-flight–mass spectrometry de...

OBJECTIVES To investigate the relative pathogenicity of Candida albicans treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis. Previous studies indicate that these cells secrete 10 times more farnesol than do untreated cells. In our usage, subinhibitory means a concentration which causes a prominent decrease in turbidity but still allows some cel...

Propolis, a resinous bee product, has been shown to inhibit the growth of oral microorganisms and the activity of bacterium-derived glucosyltransferases (GTFs). Several compounds, mainly polyphenolics, have been identified in this natural product. The present study evaluated the effects of distinct chemical groups found in propolis on the activity of GTF enzymes in solution and on the surface o...

Streptococcus mutans is the primary causative agent of dental caries, one of the most prevalent diseases in the United States. Previously published studies have shown that Pluronic-based tooth-binding micelles carrying hydrophobic antimicrobials are extremely effective at inhibiting S. mutans biofilm growth on hydroxyapatite (HA). Interestingly, these studies also demonstrated that non-binding ...

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