Background & aim: Hypertensive disorders of pregnancy are among the severe medical disorders peculiar to pregnancy. It is one of the risk factors during pregnancy either for the mother or fetus or both. Therefore, this study aimed to assess fetal and neonatal outcomes of mothers with hypertensive disorders of Pregnancy. Methods: This hospital-based cross-sectional study was conducted on neonate...

The developmental origins of disease or fetal programming model predict that early exposures to threat or adverse conditions have lifelong consequences that result in harmful outcomes for health. The maternal endocrine 'fight or flight' system is a source of programming information for the human fetus to detect threats and adjust their developmental trajectory for survival. Fetal exposures to i...

Breast cancer diagnosed during pregnancy poses unique challenges. Application of standard treatment algorithms is limited by lack of level I evidence from randomized trials. This study describes contemporary multidisciplinary treatment of pregnancy-associated breast cancer (PABC) in an academic setting and explores early maternal and fetal outcomes. A search of the Dana-Farber/Harvard Cancer Ce...

introduction: regarding to the recent advances in assisted reproductive techniques (art), twin and multiple pregnancies have increased during past years. objective: this study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following art with spontaneous pregnancy. materials and methods: in this cross-sectional study which was performed in ghaem hospital...

The effects of dengue infection during pregnancy have not been previously studied in Rio Branco, Acre State, Brazil. The aim of this study was to determine the risks of maternal, fetal, and infant complications resulting from dengue infection during pregnancy. The study compared two cohorts of pregnant women, exposed versus unexposed to dengue virus, from 2007 to 2012. Incidence rates and risk ...

OBJECTIVE To assess the ability of the member states of the European Union to produce the indicators recommended by the PERISTAT project on perinatal health indicators and to provide an overview of fetal and infant health outcomes for these countries according to the information now available. METHODS We used data from the PERISTAT survey of data providers to compute PERISTAT indicators of fe...

BACKGROUND Caesarean section is a commonly performed operation on women that is globally increasing in prevalence each year. There is a large variation in the rates of caesarean, both in high and low income countries, as well as between different institutions within these countries. This audit aimed to report rates and reasons for caesarean and associated clinical care practices amongst nine ho...

OBJECTIVE To examine fetal growth and perinatal outcomes in pregnancies with isolated oligohydramnios. DESIGN A cohort study. SETTING Multiple clinics and hospitals. POPULATION Low risk pregnant women. METHODS We used data from the multicentre clinical trial of Routine Antenatal Diagnostic Imaging with UltraSound (RADIUS), in which 15,151 low risk pregnant women were randomly assigned t...

The maternal cardiovascular system undergoes hemodynamic changes during pregnancy via angiogenesis and vasodilation to ensure adequate perfusion of the placenta. Improper vascularization at the maternal-fetal interface can cause pregnancy complications and poor fetal outcomes. Recent evidence indicates that small conductance Ca(2+)-activated K(+) channel subtype 3 (SK3) contributes to vascular ...