نتایج جستجو برای: fok1
تعداد نتایج: 77 فیلتر نتایج به سال:
BACKGROUND The exact etiology of recurrent tonsillopharyngitis in children is not clear. Recurrent tonsillitis in children has multifactorial etiology like most of the diseases in childhood. In this study, our aim was to determine the potential role of vitamin D in recurrent tonsillitis by measuring serum 25-OH vitamin D levels and determining the vitamin D receptor polymorphism among children ...
Background and purpose: Osteoporosis is a multiple disease that is characterized by decrease in bone mass and bone strength. This decrease is more common in postmenopausal women due to decreased estrogen levels. Vitamin D3 plays a pivotal role in skeletal metabolism by binding to nuclear steroid receptors (receptors for vitamin D (VDR)). This study aimed at investigating the relationship betwee...
Background & Aims: Breast cancer is one of the most common cancers worldwide and accounts for one third of all cancers in women. Vitamin D and its metabolites have a critical role in bone metabolism and any decrease in synthesis and production of this vitamin causes cancers, including breast and ovarian and colon. In this study, we examined the relationship between FOK1 and BSMI rest...
On the roles of skin type and sun exposure in the risk of endometriosis and melanoma The recent paper by Kvaskoff et al. 1 reported observations of endometriosis risk in relation to naevi, freckles and skin sensitivity to sun exposure. The study found significantly increased risk for endome-triosis for those highly sensitive to sun exposure and for those with naevi or freckles. Those with dark ...
Abundant experimental evidence provides a rationale for examining the role of vitamin D in relation to breast cancer risk. Specifically, the main actions of the biologically active form of vitamin D, 1,25(OH)2D, are mediated via the vitamin D receptor. The vitamin D receptor (VDR) is present in normal breast tissue. 1,25(OH)2D has antiproliferative effects on and promotes the differentiation of...
BACKGROUND Some epidemiological, genetic, and experimental data suggest a possible role of vitamin D in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis. Data on the possible contribution of several single nucleotide polymorphisms (SNP) in the vitamin D receptor (VDR) gene to the risk for MS are controversial. Several studies suggested an interaction ...
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