BACKGROUND Homograft valves offer many advantages; however, there is concern about their use in second aortic valve replacement because of the complexity of the procedure and the possibility of accelerated degeneration. METHODS AND RESULTS One hundred and forty-four patients underwent a second aortic homograft replacement between 1973 and 1997 (mean follow-up 6.5+/-5 years, range 1 to 20 year...

A 47-year-old patient visited our outpatient clinic. She was born with tricuspid atresia with normally connected great arteries without pulmonary stenosis (type Ic); a ventricular septal defect connected the pulmonary artery and hypoplastic right ventricle (RV) with the left ventricle. When she was 14 years old, a Fontan-Bjork procedure was performed.1 The atrial and the ventricular septal defe...

The whole serum complement and its components were studied in 24 recipients of 27 renal homografts. In 12 of 13 instances in which homograft rejection was diagnosed, it was accompanied by significant declines in CHSO, IASO, C4, and C3 levels, and to a lesser degree in C1 and C2 levels. Fourteen patients had normal graft function during the postoperative course of study, and in 13 of the 14 the ...

The literature on the subject of bone transplantation is now so voluminous (Chase and Herndon 1955) that any attempt to add to it constructively is difficult. Much of this literature attempts to compare techniques which are not strictly comparable. Either it extols the virtue of a clinical approach to the problem, excluding laboratory research, or it concentrates so much on experimental work th...

The clinical results of isolated mitral valve replacement with mounted aortic valve homografts undertaken in 29 patients is presented. In 15 of these patients haemodynamic evaluations were made before and after operation. The results attest to the haemodynamic suitability of the homograft aortic valve in the mitral position and it would appear from this initial study that there will be little d...

The effect of homograft sensitization of a mother against her fetuses has been studied. A female rabbit was repeatedly grafted from both members of a breeding pair. Their offspring should and do become objects of homograft sensitization induced in the female by grafts from the parents. After sensitization was established, fertilized ova were transplanted from the breeding pair to the sensitized...

To assess the results of cardiac repair utilizing a right ventricular to pulmonary artery conduit, we reviewed postoperative hemodynamic data in 16 patients catheterized 0.5 to 5 years after repair. In 12 patients, a Hancock conduit (dacron conduit with porcine valve) was used; the conduit in the remaining four patients was made with an aortic homograft. All patients in whom an aortic homograft...