A 27-year old female patient, born and living in Morocco, suffered from severe variceal bleeding and weight loss. Eventually a diagnosis of gastric fundus varices was made supposedly resulting from partial obstruction of the splenic vein and collateral blood flow via the short gastric veins. Splenectomy was proposed. Peroperatively it became apparent that a solitary ecchinococcal cyst in the hi...

The effect of 28 days' continuous administration of oral indomethacin on gastroduodenal morphology, gastric mucosal blood flow, and gastric mucosal prostaglandin E2 (PGE2) metabolism in man was studied to define further the mechanisms of mucosal injury induced by indomethacin. Indomethacin caused acute gastroduodenal damage in all cases, which was maximal at 24 hours of administration. With con...

Ischemic preconditioning is considered as the most powerful gastroprotective intervention against mucosal lesions and ulcerations but the mechanism of this phenomenon has been little examined. In this study we tested the effects of inactivation of sensory nerves in new rat model combining acute gastric erosions with subsequent ulcers induced by ischemia-reperfusion (I/R). I/R lesions were produ...

MOODY, FRANK G. Oxygen consumphn during thiocyanate irhibition of gastric acid secretion in dog. Am. J, Physiol. 2 15( 1) : 127-131. 1968.-The relationship between oxygen c&sumption, blood flow, and acid secretion was studied in exteriorized gastric se gments of the dog during histamine and thiocyanate administration. Acid secretion and oxygen consumption demonstrated a highly significant linea...

BACKGROUND/AIMS Intratumoral hemodynamics or tumor perfusion is useful in understanding the pathological background of the cancer. A parameter for a non-invasive, preoperative assessment of tumor perfusion has yet to be developed. METHODS The study included 50 patients who underwent surgery for gastric cancer. Perfusion computed tomography (P-CT) was performed using a 16-row multidetector CT,...

conclusions results suggest that these methods cannot be interchanged, and vvi showed significantly lower lv peak twist, peak twisting rate and peak untwisting rate. however, when lv twist and lv twisting rates were normalized to lv length, values were comparable for both imaging techniques. results twist degree was significantly lower in the vvi group than in the tdi group (p = 0.008, r = 0.56...

Epidemiological studies have shown that cigarette smoking is associated with peptic ulceration. This study aims to investigate the mechanisms by which cigarette smoking delays ulcer healing in rats. Gastric ulcers were induced by applying acetic acid to the luminal surfaces in rats. Twenty-four hours later, rats were exposed to different concentrations of cigarette smoke (0, 2, or 4%) for a 1-h...