central giant cell granulomas (cgcgs) may manifest as radiolucencies anywhere in the mandible or maxilla. in rare cases, it can appear as a localized periradicular area and mimic an endodontic lesion. this case report presents an uncommon location of cgcg which was not accurately diagnosed nor timely treated. periodic follow ups of periapical radiolucencies after rct are necessary. dentists sho...

the b cell is a vital contributor to humoral immunity. the b cell-specific antigen cd20 is expressed during b cell development, starting at the pre-b cell level and persists through b cell differentiation, but is lost during terminal differentiation to plasma cells. rituximab is a monoclonal antibody that destroys both normal and malignant b cells that have cd20 on their surfaces and is therefo...

introduction: giant cell lesions of the bone comprise a group of jaw bone pathologies. different pathogeneses such as reactive, vascular or neoplastic have been proposed for these lesions. in addition, differentiating between aggressive and nonaggressive central giant cell granuloma (cgcg) of the jaws based on histopathologic features is still impossible and due to different treatment protocols...

in view of the rapid expansion of contact lens amongst the users, new dimensions have been added to the domain of ophthalmology: giant papillay conjunctivitis, a disease caused by different kinds of contact lens, appears weeks or months after they are used, although some patients are struck years later. the predominant symptoms are increased awareness of lenses, ocular itching, blurred vision a...

introduction bladder diverticulum is a result of bladder mucosa and submucosa herniation through the muscularis propria of bladder wall. bladder diverticula are mostly seen in the elderly men in association with benign prostatic hyperplasia (bph). case presentation a 74-year-old man presented with complaints of vague epigastric discomfort, dyspepsia, and mild lower urinary tract symptoms. an ul...

conclusions this case indicates that delineation of coronary artery anatomy in atypical congenital giant right atrial aneurysm is of vital importance. closure of the aneurysmal sac, instead of aneurysmal resection, is a safer and more simple approach in atypical cases. case presentation this is a report on a 3.5-month-old male infant with imperforated anus and an unusual-shaped congenital giant...

central giant cell granuloma (cgcg), formerly called giant cell reparative granuloma, is a non-neoplastic proliferative lesion of unknown etiology. it occurs most commonly in the mandible. the case reported here resembled a wide variety of conditions that led to a misdiagnosis both on clinical and radiographic examinations but was histopathologically diagnosed as cgcg. we describe a case of cgc...

  Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal ...

Idiopathic thrombocytopenia purpura (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia and mucocutaneous bleeding. The former has a primary role in the diagnosis and treatment of ITP. One of the leading causes of miscounted platelets in patients who suffer from ITP is giant platelets which may indicate factitiously a severe false thrombocytopenia. Here, a case of macroth...