Human anatomical models have been indispensable to radiation protection dosimetry using Monte Carlo calculations. Existing MIRD-based mathematical models are easy to compute and standardize, but they are simplified and crude compared to human anatomy. This article describes the development of an image-based whole-body model, called VIP-Man, using transversal color photographic images obtained f...

A t the SNMMI Annual Meeting on June 14th in San Diego, CA, Joseph A. O’Donoghue, PhD, of Memorial Sloan–Kettering Cancer Center (New York, NY), received the 2016 Loevinger–Berman Award for his contributions to understanding of the radiobiology of targeted radionuclide therapy. The Loevinger–Berman Award is given annually by the SNMMI Medical Internal Radiation Dose (MIRD) Committee in honor of...

To determine quantities for radiation protection against high-energy electrons, such as those from LINAC, the organ dose equivalents and equivalent doses for the human body were calculated using EGS-4 Monte Carlo simulation code and an MIRD-5 mathematical human phantom. Conversion factors for the incident fluence to the organ dose equivalent, to the effective dose and to the effective dose equi...

Abstract. The goal of this project is to determine the absorbed dose of radiation to a patient using 99mTc-MAA as a tracer for a lung scan using the MIRD formula accounting only for the radiation dose contributed by the target organ. The radiation dose for other organs to the target organ is considered negligible as the uptake of 99mTc-MAA from other organs is less than 1%. In addition to calcu...

long-term mechanical circulatory support is a life-saving technology while briding to heart transplantation. it increases the quality of life and preserves end-organ function for patients with  advanced heart failure. the number of patients with advanced heart failure scheduled for heart transplantation before comorbidities escalate is on the rise. however, the device function is complicated by...

This study demonstrates the normal technetium-99m diethylenetriaminepentaacetic acid ([99mTc]DTPA) renal scan in pregnant patients with transplanted kidneys. Five pregnant renal transplant patients had seven [99mTc]DTPA renal studies to assess allograft perfusion and function. All scans showed the uteroplacental complex. The bladder was always compressed and distorted. The transplanted kidney w...

Abstract Purpose A 2-m axial field-of-view, total-body PET/CT scanner (uEXPLORER) has been recently developed to provide coverage and ultra-high sensitivity, which together, enables opportunities for in vivo time-activity curve (TAC) measurement of all investigated organs simultaneously with high temporal resolution. This study aims at quantifying the cumulated activity patient dose 2-[F-18]flu...