نتایج جستجو برای: hep2 cell line

تعداد نتایج: 1969313  

Journal: :archives of razi institute 2016
s. masoudi

in this syudy a continuous bovine kidney cell line derived from a primary bovine kidney cells was established for the first time in iran. the cells were originating from two-day-old normal male calf of holstein breed. the cell cultures were continuously passaged following complete proliferation of primary cells. the specific properties or characteristics of the cell were defined using cytogene...

Journal: :Indian journal of experimental biology 2000
U Tuteja H V Batra

Monoclonal antibodies (MoAbs) were generated following immunization of Balb/C mice with adenovirus type 5 grown in Hep2 cell line. Six clones reactive to hexon antigen of the virus were stabilized, of which 4 had mu-heavy chain specificity and 2 were of gamma-heavy chain type. Three of the clones (ADV-1, ADV-3 and ADV-5) had a high ELISA reactivity to the hexon antigen but exhibited differentia...

Journal: :iranian journal of blood and cancer 0
mehryar habibi roudkenar mahshid mohammadipour arezou oodi raheleh halabian naser amirizadeh nasser masrouri

background: the rh antigens are expressed as parts of a protein complex in the rbc membrane. this complex is a tetramer, consisting of two molecules of rhag and two molecules of rh proteins. to express rhd in rbc membrane, expression of rhag is essential. this co-expression only occurs in the erythroid lineage. k562 cell line has an erythroid lineage. materials and methods: cord blood was used ...

Journal: :Neoplasma 1997
M Osmak I Kovacek I Ljubenkov R Spaventi M Eckert-Maksić

The role of ascorbic acid (AA) in prevention and suppression of carcinogenesis has been known for a long time. It was also found that AA may inhibit the growth of some tumor cells in vitro and in vivo. We examined the influence of ascorbic acid and 6-chloro-6-deoxy ascorbic acid (6-Cl-AA) on the growth of various human cell lines: lung fibroblasts (Hef), ovarian adenocarcinoma (OVCAR), colon ad...

Journal: :iranian journal of pharmaceutical research 0
bardia jamali biopharmaceutics and pharmacokinetics division, department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran. maryam nakhjavani department of toxicology & pharmacology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. leila hosseinzadeh toxicology and pharmacology department, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran. salimeh amidi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. nastaran nikonezhad department of toxicology, sbmu pharmacy school, tehran, iran. farshad h. shirazi sbmu pharmaceutical sciences research center, p.o.box 14155-3817, tehran, iran.

one of the major complications in cancer chemotherapy is the development of resistance, and cisplatin, as one of the important medicines in treatment regimens of different cancers is not excluded. one of the most described cellular defense mechanisms involved in resistance is glutathione (gsh) and in this study, the effects of cisplatin on the total intracellular gsh level (gshi) in some sensit...

Journal: :The Journal of clinical investigation 1992
D M Bass M R Baylor C Chen E M Mackow M Bremont H B Greenberg

Rotaviruses are an important cause of gastroenteritis in human infants. In vivo, rotavirus displays striking cell tropism with viral replication generally restricted to the villus tip enterocytes of the small intestine. We studied a panel of cell lines that vary significantly in their permissivity to rotavirus infection. L cells and HEp2 cells were relatively resistant to rotavirus infection co...

Journal: :Journal of virology 2011
Kari L Roberts Joel D Baines

Previous results suggested that the U(L)31 gene of herpes simplex virus 1 (HSV-1) is required for envelopment of nucleocapsids at the inner nuclear membrane and optimal viral DNA synthesis and DNA packaging. In the current study, viral gene expression and NF-κB and c-Jun N-terminal kinase (JNK) activation of a herpes simplex virus mutant lacking the U(L)31 gene, designated ΔU(L)31, and its gene...

Journal: :iranian journal of basic medical sciences 0
seyedeh alia moosavian biotechnology research center, nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran mahmoud reza jaafari biotechnology research center, nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran seyed mohammad taghdisi targeted drug delivery research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran fatemeh mosaffa biotechnology research center, pharmacy school, mashhad university of medical sciences, mashhad, iran ali badiee nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran khalil abnous pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. human epidermal growth factor receptor 2 (her2) is specifically expressed on the surface of breast cancer cells. her2 is associated with an aggressive phenotype and poor prognosis. in this study we aimed to isolate rna aptamers that specifically bind to her2 overexpressi...

Journal: :Clinical chemistry 1992
R Makiya T Stigbrand

We review data from our studies of the physiological role of placental alkaline phosphatase (PLAP) and report that, in addition to functioning in catalysis, PLAP has the capacity to bind the Fc portion of human IgG. The dissociation constant for the interaction (3.86 mumol/L) indicates that the PLAP-IgG complex probably occurs in vivo. Furthermore, the electrophoretic and immunochemical propert...

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