Methionine sulfoxide reductase A (MsrA) catalyzes the reduction of methionine sulfoxide to methionine and is specific for the S epimer of methionine sulfoxide. The enzyme participates in defense against oxidative stresses by reducing methionine sulfoxide residues in proteins back to methionine. Because oxidation of methionine residues is reversible, this covalent modification could also functio...

Many patients use herbal supplements to treat chronic cardiovascular conditions and often combine herbal ingredients with cardiovascular medications. However, physicians do not reliably elicit a history of herbal use from their patients and may overlook herbal supplements' adverse effects. Although often considered harmless by patients, herbal supplements may cause adverse cardiovascular effect...

The endotelio- and cardioprotective effects of vitamin B6 (2 mg/kg) folic acid (0.2 upon modeling methionine-induced hyperhomocysteinemia via methionine intragastric administration at a dose 3 g/kg were studied. It was shown that the combined use allows on background significant reduction in homocysteine concentrations normalizing endothelial dysfunction coefficient parameters maximum left vent...

Use of herbal medicine in the treatment of liver cancer has a long tradition. The compounds derived from the herb and herbal composites are of considerable interest among oncologists. In the past, certain herbal compounds and herbal composite formulas have been studied through in vitro and in vivo as an anti-hepatocellular carcinoma (HCC) agent, enhancing our knowledge about their biologic func...

Methionine is an amino acid that extremely important for human health. To better understand the biochemical events occurring in body, excess molar properties of methionine and aqueous ethanol methanol mixtures were determined at 298.15 K. Interactions between components solutions are explained. Negative deviations from ideal state have been observed due to hydrogen bonds, dipole interactions, c...

Introduction: Feathers are important body structures that act as surface insulators to reduce maintenance energy requirements and also to protect skin against abrasions and infection. The purpose of this study is to investigate the effects of methionine injection into the yolk sac on development of feather follicle in chicken embryo. Methods: 50 fertilized eggs (weighting 50±0.4 gr) of Ross×...

Methionine has an almost unique stimulatory effect on biosynthesis of cephalosporins (by Cephalosporium acremonium). No other sulfur-containing compound tested, except dl-methionine-dl-sulfoxide, replaced methionine. dl-Methionine stimulated the synthesis of cephalosporins when added after the growth phase. The utilization of inorganic sulfate was repressed by methionine. Experiments with l-met...