We report Langerhans cell histiocytosis involving the sphenoid sinus and extending to the orbital apex. MR and CT imaging, particularly with contrast, both were helpful in defining the extent of the lesion before treatment. MR was a useful examination for follow-up after treatment. Langerhans cell histiocytosis should be considered in the differential diagnosis of lesions of this region in the ...

Malignant histiocytosis (histiocytic medullary reticulosis) in a 45-year-old white man is described. Unusual features were presentation as a surgical emergency with signs of obstruction and peritonitis due to an ileal tumour and extensive spindle cell differentiation. Problems in the differential diagnosis of malignant histiocytosis are briefly discussed.

Pulmonary Langerhans cell histiocytosis is a rare interstitial lung disease. It's morbidity is estimated at 4-5 person per million. The multiformity--from benignity to severe--brings difficulties during the process of diagnosis. The authors describe a case of 48-year-old woman with a benign pulmonary lung histiocytosis. It is underlined the diagnostic quality of high resolution tomography and b...

Severe skin involvement complicated a case of sinus histiocytosis with massive lymphadenopathy in a young Malay girl. The clinical and histological features of this rare manifestation are described.

Background Langerhans cell histiocytosis (LCH) is a rare disease in which monoclonal migration and proliferation of specific dendritic cells is seen. The disease primarily affects the bones and skin, but there is a possibility that involves other organs or appears as a multi-systemic disease. Case Report In oral examination of a nine-month girl, two deep wounds with a yellow membrane with appro...