نتایج جستجو برای: histones
تعداد نتایج: 6224 فیلتر نتایج به سال:
We previously discovered histones bound to cytosolic lipid droplets (LDs); here we show that this forms a cellular antibacterial defense system. Sequestered on droplets under normal conditions, in the presence of bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA), histones are released from the droplets and kill bacteria efficiently in vitro. Droplet-bound histones also function in v...
1. The incorporation of methyl groups into histones from dimethylnitrosamine and from methionine was studied by injection of the labelled compounds, isolation of rat liver and kidney histones, and analysis of hydrolysates by column chromatography. 2. Labelled methionine gave rise to labelled in-N-methyl-lysine, di-in-N-methyl-lysine and an amino acid presumed to be omega-N-methyl-arginine. 3. A...
The transcription of DNA is known to be inhibited in vitro by the presence of histones. This has been shown to be true for isolated nuclei, isolated chromatin, or for DNA alone (Bonner & Huang, 1962; Bonner, Huang & Gilden, 1963; Allfrey & Mirsky, 1963; Allfrey, Faulkner & Mirsky, 1964; Sonnenberg & Zubay, 1965). The masking of genomic sites in adult differentiated tissues seems the most probab...
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