The interaction of sodium n-dodecyl sulphate (SDS) with histones in phosphate buffer pH 6.4 has been studied spectroscopically and by equilibrium dialysis. The enthalpies of interaction and the spectroscopic data suggest different structural stability for histones-SDS interaction. The linear relation between enthaly and absorbtion was determined by the equation of m= , where m is the sta...

isotherms of the binding of the anthracyciine antibiotic, adriamycin (adriblastin), to dna histone complexes was studied by means of spectroscopic analysis. the results indicated that: (a) binding of adriamycin to histones reduced the interaction of histones with dna, (b) binding of the drug to dna did not change the binding affinity of histone to dna and, (c) in the explored binding range of r

the interaction of sodium n-dodecyl sulphate (sds) with histones in phosphate buffer ph 6.4 has been studied spectroscopically and by equilibrium dialysis. the enthalpies of interaction and the spectroscopic data suggest different structural stability for histones-sds interaction. the linear relation between enthaly and absorbtion was determined by the equation of m= , where m is the stability ...

Post-translational modifications of histones are essential in the regulation chromatin structure and function. Among these modifications, lysine acetylation is one most established. Earlier studies relied on use containing heterogeneous mixtures acetylated at multiple sites. Differentiating individual contribution single events towards thus great relevance. However, it difficult to access homog...

JAUNDICE DURING PREGNANCY. By Urs Peter Haemmerli. New York, Springer-Verlag, Inc., 1967. 111 pp. $3.80, paperbound. Jaundice During Pregnancy is an excellent monograph which should be read by all internists, obstetricians, and pediatricians, and which should be available in all medical libraries for ready reference. The author concisely summarizes the known minor alterations of the liver and i...