We study the dynamical exponent z for the directed percolation depinning (DPD) class of models for surface roughening in the presence of quenched disorder. We argue that z for d 1 1 dimensions is equal to the exponent dmin characterizing the shortest path between two sites in an isotropic percolation cluster in d dimensions. To test the argument, we perform simulations and calculate z for DPD, ...

Anthracycline-resistant HL-60/AR cells and their drug-sensitive HL-60/S counterparts were characterized by karyotypic analysis and examined for the overexpression of DNA and mRNA sequences coding for P-glycoprotein (Pgp). The HL-60/S cells were karyotypically stable over a 5-year period of study (1986-1991), except for an additional small Giemsa-positive band noted at 7q22 in cultures harvested...

In order to compare the performances of three transmission schemes of keyinterest able to reach the maximum diversity order, guarantee of robust transmission, we used a dual-polarization channel model to take into account polarization diversity and transmit/receive correlation. These schemes under study were i)two systems using full channel state information (CSI) at the transmitter side (Tx-CS...

Plasmids with both a mammalian replication initiation region (IR) and a matrix attachment region (MAR) are spontaneously amplified in transfected cells, and generate extrachromosomal double minute (DM) or chromosomal homogeneously staining region (HSR). We previously isolated the shortest core IR (G5) required for gene amplification. In this study, we ligated the G5 DNA to create direct or inve...

A graph G = (V, E) is called a pairwise compatibility graph (PCG) if there exists a tree T , a positive edge-weight function w on T , and two non-negative real numbers dmin and dmax, dmin ≤ dmax, such that V coincides with the set of leaves of T , and there is an edge (u, v) ∈ E if and only if dmin ≤ dT,w(u, v) ≤ dmax where dT,w(u, v) is the sum of the weights of the edges on the unique path fr...

PURPOSE MYCN amplification in neuroblastoma tumor cells is manifested primarily as double minutes (dmins), whereas in cell lines it often appears in the form of homogeneously staining regions (HSR), suggesting that HSRs are associated with a more aggressive tumor phenotype and worse clinical outcome. The aim of this study was to determine whether children with neuroblastoma in which MYCN oncoge...

In this paper we introduce homogeneously orderable graphs which are a common generalization of distance-hereditary graphs, dually chordal graphs and homogeneous graphs. We present a characterization of the new class in terms of a tree structure of the closed neighborhoods of homogeneous sets in 2-graphs which is closely related to the defining elimination ordering. Moreover, we characterize the...

The mechanisms of gene amplification in tumour cells are poorly understood and the relationship between extrachromosomal DNA molecules, named double minutes (dmins), and intrachromosomal homogeneously staining regions (hsr) is not documented at nucleotide resolution. Using fluorescent in situ hybridization and whole genome sequencing, we studied a xenografted human oligodendroglioma where the c...