OBJECTIVE Atypical antipsychotic drug treatment is clinically effective with a low risk of extrapyramidal symptoms. Explanations for the mechanism underlying this beneficial therapeutic profile of atypical over typical antipsychotic agents include 1) simultaneous antagonism of dopamine D(2) and serotonin 5-HT(2A) receptors or 2) selective action at limbic cortical dopamine D(2)-like receptors w...

Although the favourable characteristics of escitalopram as being the most selective serotonin reuptake inhibitor and having an increased therapeutic efficacy via binding on an additional allosteric binding site of the serotonin transporter, its dosing regimen has not yet been optimized for its use in dogs. This study aimed to estimate the optimal dosing frequency and the required dose for achie...

to study the effects of priming on seed germination traits of sainfoin 'eski', a factorial in randomized complete block design with three replications was conducted at the laboratory of agricultural research center of sari in 2011. treatments consisted of polyethylene glycol (peg6000) at 5 and 10%, potassium nitrate (kno3) at 5 and 10% and potassium chloride (kcl) at 5 and 10% levels ...

Training for Our Volumetric CNNs To produce occupancy grids from meshes, the faces of a mesh are subdivided until the length of the longest edge is within a single voxel; then all voxels that intersect with a face are marked as occupied. For 3D resolution 10,30 and 60 we generate voxelizations with central regions 10, 24, 54 and padding 0, 3, 3 respectively. This voxelization is followed by a h...

BACKGROUND hospitals are under pressure to reduce waiting times and costs. One strategy that may be effective focuses on optimising the flow of emergency patients. OBJECTIVE we undertook a patient flow analysis of older emergency patients to identify and address delays in ensuring timely care, without additional resources. DESIGN prospective systems redesign study over 2 years. SETTING th...

The Earnings, Hours and Employment Costs Survey (EHECS) captures information each quarter on total earnings, paid hours and level of employment from a large representative sample of employers. Responses received typically cover more than 70% of all employees in the state. The main purpose of the survey is to gauge trends in the average level of earnings and hours worked over time across all sec...

Safe and appropriate health care, especially in urgent or emergency situations, is the expectation of the public throughout the developed world. Achieving this goal requires appropriate levels of medical and other staff, appropriate training, and sensible working hours. Too often the brunt of such care, especially in out-of-hours situations, is borne by medical residents, who--to make matters w...

We investigated the extent to which the safety performance (i.e., self-reported safety compliance and safety participation) of employees with 2 jobs was predicted by their respective supervisors' transformational leadership behaviors. We compared 2 within-person models: a context-specific model (i.e., transformational leadership experienced by employees in 1 context related to those same employ...