Both the I (independent of glucose 6-phosphate) and D (dependent on glucose 6-phosphate) forms of glycogen synthase (UDP-glucose:glycogen alpha-4-glucosyltransferase EG 2.4.1.11) have been partially purified from pig brain and the kinetic constants of the enzymes have been examined. The Km for UDP-glucose for the I form increased from 0.11 to 0.5 mM when the temperature was raised from 25 to 37...

William Osler is quoted as saying, "Nothing will sustain you more potently than the power to recognize in your humdrum routine, as perhaps it may be thought, the true poetry of life-the poetry of the commonplace, of the plain, toil-worn woman, with their loves and their joys, their sorrows and their griefs."(1) A family physician reflects how he continues to derive sustenance from having cared ...

There are 600 million betel quid (BQ) chewers in the world. BQ chewing is a major etiologic factor of oral cancer. Areca nut (AN) and arecoline may inhibit the growth of oral mucosal fibroblasts (OMF) and keratinocytes. In this study, AN extract (100-800 microg/ml) and arecoline (20-120 microM) inhibited the growth of oral KB cells by 36-90 and 15-75%, respectively. Exposure to arecoline (> 0.2...

This study was to evaluate the interfractional and intrafractional setup errors and baseline shifts of golden fiducial markers in patients receiving postoperative radio- therapy (RT) using cone-beam computed tomography (CBCT) in order to calculate PTV margins for patients with liver cancer. Twelve patients with liver tumors under- went postoperative RT. CBCT images were acquired before and afte...

BACKGROUND Diffusion-weighted magnetic resonance imaging (DWI) is a widely-accepted diagnostic modality whose efficacy has been investigated by numerous past studies in the differentiation of malignant lesions from benign entities. AIMS The aim of this study was to evaluate the efficiency of diffusion-weighted magnetic resonance imaging in the characterization of renal lesions. STUDY DESIGN...

computed tomography-based 3-dimensional cross-sectional moment and cross-sectional moment of inertia Tobita, K; +Ohnishi, I; Matsumoto, T; Ohashi, S; Bessho, M; Kaneko M; Matsuyama, J; Nakamura, K + Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan [email protected] INTRODUCTION Low-intensity pulsed ultrasound stimulation (LIPUS) reportedly enh...

The present study was conducted in order to investigate the effect of salicylic acid on growth, yield and macro-elements absorption of fennel in split-plot as base on randomized complete block design (RCBD) with three replications in Tehran, Iran. Irrigation regime as main plot was undergone in 5 levels that included: I1: full irrigation, I2: cut off irrigation at stem elo...

This account of her experiences as a patient in a mental hospital has been sent to Mental Health by Susan X. We cannot, of course, print her name in full.

The stability of nucleosomes of SV40 minichromosomes extracted from infected cells or reconstituted by association of SV40 DNA and the four histones H2A, H2B, H3 and H4 was studied as a function of the ionic strength. As a measure of the stability of the nucleosome, we followed the disappearance of the nucleosomes from the original chromatin and their appearance on a "competing" DNA. We show he...