Background: One of the most important issues for patients with osteoarthritis is reducing pain and returning them to normal life. In addition to losing weight and improving daily activities, pain management treatments may be needed. One of these treatments is the injection of hyaluronic acid gel into the knee joint, which has been studied in this study. Methods: In this stud...

Objective. This present study aimed to explore the clinical effects of ultrasound-guided (USG) mechanical needling with sterile water injection for lumbar facet joint syndrome. Methods. was a retrospective cohort that assessed outcome ageing patients who received USG injection. In addition, age- and gender-matched randomly selected from compared injected steroids in 2 : 1 ratio. The data were e...

INTRODUCTION This study was performed to investigate the effect of topical anesthesia on pain during needle penetration and infiltration injection as well as the effect of pain during injection on success rate of anesthesia in maxillary central incisors. METHODS In a crossover double-blind study, 25 volunteers randomly received either topical anesthesia or placebo before infiltration injectio...

Based on the available evidence, the Therapeutics and Technology Assessment subcommittee concluded that 1) epidural steroid injections may result in some improvement in radicular lumbosacral pain when assessed between 2 and 6 weeks following the injection, compared to control treatments (Level C, Class I–III evidence). The average magnitude of effect is small and generalizability of the observa...

Background: Propofol is the most commonly used induction agent, but causes pain on injection in many patients. Various techniques have been tried and tested for reducing pain due to propofol injection with different results. Objective: To compare the use of pretreatment with granisetron in comparison with lignocaine in reducing pain on propofol injection. Patients and Methods: 104 patients (ASA...

background: this double-blinded, randomized clinical trial was designed to evaluate the comparison of intravenous versus intraarticular (ia) administration of midazolam on postoperative pain after knee arthroscopy. materials and methods: in this study, 75 patients randomized in three groups to receive 75 mc/kg ia injection of midazolam and 10 ml intravenous injection of isotonic saline (group i...

In this study, the effects of subcutaneous (SC) injection of pilocarpine (a cholinomimetic agent) and atropine (a muscarinic receptors antagonist) were investigated on a tonic model of orofacial pain in rats. The contribution of the endogenous analgesic opioid system was assessed using naloxone (an opioid receptors antagonist). Tonic orofacial pain was induced by SC injection of a diluted forma...

PURPOSE To investigate whether the rate of infiltration of local anaesthetic influences the pain or efficacy of local anaesthesia in oculoplastic surgery. METHODS A prospective observational study on consecutive patients undergoing a variety of oculoplastic procedures under local anaesthesia. An observer recorded the rate of injection of local anaesthetic during each procedure. The same mixtu...

AIM The primary objective of this study was to evaluate the impact of fluid injection viscosity in combination with different injection volumes and flow rates on subcutaneous (SC) injection pain tolerance. METHODS The study was a single-center, comparative, randomized, crossover, Phase I study in 24 healthy adults. Each participant received six injections in the abdomen area of either a 2 or ...