A mycotic aneurysm of the superior mesenteric artery caused by Enterococcus faecalis was successfully treated with aneurysmectomy and reconstruction a bifurcated saphenous vein graft. 49-year-old man history type 2 diabetes mellitus recent left transmetatarsal amputation for osteomyelitis presented to emergency department severe abdominal pain, an unexplained 30-lb weight loss, wound dehiscence...

Artery reconstruction in upper extremities is rare performed compared to artery reconstruction in lower extremities. Primary vascular repair was performed in many cases. An interposition vein graft or venous bypass grafting were applied in order to alleviate thrombus in blood vessel. However, one or more of the applied vein graft are blocked or severely narrowed due to the mismatched internal d...

The aim of this study was to detect the inhibitory action of the early growth response gene-1 DNA enzyme (EDRz) as a carrying agent by liposomes on vascular smooth muscle cell proliferation and intimal hyperplasia. An autogenous vein graft model was established. EDRz was transfected to the graft vein. The vein graft samples were obtained on each time point after surgery. The expression of the E...

OBJECTIVE To accelerate vein graft reendothelialization and reduce vein graft thrombosis by infusing human umbilical cord blood-derived endothelial cells (hCB-ECs) because loss of endothelium contributes to vein graft thrombosis and neointimal hyperplasia. METHODS AND RESULTS Under steady flow conditions in vitro, hCB-ECs adhered to smooth muscle cells 2.5 to 13 times more than ECs derived fr...

BACKGROUND Neointima formation and atherosclerosis compromise long-term graft patency in aortocoronary and peripheral vein bypass grafts. We investigated the short- and long-term effects of periadventitial application of a sustained-release formulation of rapamycin on experimental pig vein grafts with similar dimensions and kinetics to human saphenous vein bypass grafts. METHODS AND RESULTS P...

PURPOSE Saphenous vein graft disease (SVGD), defined as an occlusion of 50% or more of the SVG excluding distal anastomotic occlusion, is an important predictor of morbidity after coronary artery bypass grafting (CABG). Late graft occlusion is a serious complication that often limits the use of the saphenous vein as a coronary bypass graft. Late graft occlusion is particularly common in old, de...

The saphenous vein is one of the most commonly used conduits during coronary artery bypass grafting. Saphenous vein graft markers have been introduced to facilitate coronary angiography procedures in the follow-up of patients with ischaemic heart disease. However, today these markers have only a historical aspect. This report presents a 61-year-old patient who had undergone coronary artery bypa...

OBJECTIVE Vein graft remodeling and neointimal hyperplasia involve inflammation, graft-intrinsic cells, and recruitment of vascular progenitor cells. We sought to examine if the inflammatory cytokine tumor necrosis factor (TNF) affects vein graft remodeling via its p55 TNF receptor-1 (p55). METHODS AND RESULTS Inferior vena cava-to-carotid artery interposition grafting was performed between p...