background and purpose: hila-g is an immunomodulatory molecule and alteration of its expression is prevalent during viral infections. hla-g expression in hiv-positive patients has been inconsistent between different studies and some suggest that interleukin-10 (il-10) influences the expression of hla-g. the aim of this research was to investigate the expression of il-10 in hiv-positive patients...

Abstract Background Interleukin (IL)-10 is one of the key interleukins in immune system. It plays an anti-inflammatory role body by inhibition synthesis pro-inflammatory cytokines and reducing expression major histocompatibility complex II molecules. The single-nucleotide polymorphism gene this interleukin affects its level. Thus, study was conducted to investigate IL-10 at position -1082A/G Az...

Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adultallergic asthma has been studied. Objective: To explore IL...

Introduction The purpose of this study was to determine the effect resistance exercise (RE)-induced hormonal changes on intramuscular cytokine gene expression after muscle damage in untrained men and women. Methods Men (n = 8, 22 ± 3 yr) women 19 1 completed two sessions 80 unilateral maximal eccentric knee extensions followed by either an upper body RE bout (EX) or a time-matched period (CON)....

mendelian susceptibility to mycobacterial diseases (msmd) is a rare inheritance syndrome, characterized by a disseminated infection with mycobacterium in children following bcg vaccination at birth. regarding the vaccination program in iran, it may consider as a public health problem. the pathogenesis of msmd is dependent on either insufficient production of ifn-gamma (γ) or inadequate response...

vitiligo is a pigmentation disorder in which inflammatory mediators such as cytokines have a pivotal role in disease's pathogenesis. interleukin 17 (il-17a) is a proinflammatory cytokine which is involved in the induction of several proinflamatory mediators such as cyclooxygenase 2 (cox2). the aim of this study was to investigate the gene expression of il-17 and cox2 in peripheral blood leukocy...

Objective(s): Interleukin-36 receptor antagonist (IL-36Ra) is a new member of the IL-1 family that exhibits anti-inflammatory activity in a variety of inflammatory and immune diseases. Our purpose was to determine the effect of IL-36Ra on liver injury in a mouse hepatitis model induced by concanavalin A (ConA). Materials and Methods: Mic...