Pentosan polysulfate (PPS) is a heparin-like polysaccharide that can affect the binding interactions of fibroblast growth factor (FGF-2) with its high-affinity receptors. Patients with angiogenic tumors frequently show high levels of FGF-2 in the circulation. Since FGF-2 is a heparin-binding angiogenic growth factor, PPS has been used successfully to block its activity in patients with angiogen...

Acute or chronic abdominal pain can be the result of many different pathophysiological processes. Many presentations are due to benign processes, whereas others may be life threatening if not recognised swiftly. Among the many possible causes, clinicians need to consider the possibility of intestinal ischaemic disorders. The variable vessels involved, location of bowel affected, and different l...

the seed of croton tiglium l. (sct) is a well known folk medicine. in china, it has used to treat gastrointestinal disorders, intestinal inflammation, rheumatism, and so on. previous studies established its purgative and inflammation properties. in addition, the effects of essential oil of sct on intestinal transit and gastrointestinal tract has been studied. in the present study, we evaluated ...

For decades, interactions between the enteric neuromuscular apparatus and the central nervous system have served as the primary focus of pathophysiological research in the functional gastrointestinal disorders. The accumulation of patient reports, as well as clinical observations, has belatedly led to an interest in the role of various luminal factors and their interactions with each other and ...

BACKGROUND Psychiatric disorders are common in chronic disease states; intestinal transplantation recipients may therefore be at high risk for psychiatric disorder (PD). We sought to investigate the frequency and type of PD in our cohort of patients undergoing transplantation between 2007 and 2012. RESULTS The notes of 25 patients who had undergone transplantations since 2007 were available f...