[Purpose] The purpose of the present study was to investigate if lactate thresholds in rats could be accurately determined during downhill running in rats. [Subjects] Twenty-four female Wistar rats were used in this study. Rats were randomly divided into two groups: the level running group and downhill running group. [Methods] Catheters were inserted into the right external jugular veins of the...

Dobson JL. Evaluation of a virtual physiology of exercise laboratory program. Adv Physiol Educ 33: 335–342, 2009; doi:10.1152/ advan.00040.2009.—The Virtual Physiology of Exercise Laboratory (VPEL) program was created to simulate the test design, data collection, and analysis phases of selected exercise physiology laboratories. The VPEL program consists of four modules: 1) cardiovascular, 2) ma...

To understand the meaning of the lactate threshold (LT) and to test the hypothesis that endurance training augments lactate kinetics [i.e., rates of appearance and disposal (Ra and Rd, respectively, mg·kg(-1)·min(-1)) and metabolic clearance rate (MCR, ml·kg(-1)·min(-1))], we studied six untrained (UT) and six trained (T) subjects during 60-min exercise bouts at power outputs (PO) eliciting the...

Excess CO2 is generated when lactate is increased during exercise because its [H+] is buffered primarily by HCO-3 (22 ml for each meq of lactic acid). We developed a method to detect the anaerobic threshold (AT), using computerized regression analysis of the slopes of the CO2 uptake (VCO2) vs. O2 uptake (VO2) plot, which detects the beginning of the excess CO2 output generated from the bufferin...

The aims of the present study were to assess gender differences regarding lactate threshold and intermittent shuttle run performance in female and male soccer players as well as to investigate the relationships between both endurance characteristics in both genders. Fourteen female (1(st) division) and thirteen male (4(th) division) soccer players completed an incremental test (IT) to determine...

OBJECTIVES Severe damage to skeletal muscle is usually seen in patients with exertional heatstroke. Thirty seven young military recruits with exertional heatstroke in Taiwan from 1992 to 1995 were studied to evaluate changes in muscle pathology and blood lactate with exercise. METHODS A biopsy sample of the vastus lateralis was taken from recruits within 10 days of the initial presentation. R...

Several methods are used for estimating the anaerobic threshold (AT) during exercise. The aim of the present study was to compare AT values based on blood lactate measurements with those obtained from computerised calculations of different respiratory gas indices. Twelve healthy, well-trained men performed a stepwise incremental test on both treadmill and cycle ergometer. Respiratory gases were...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469 1. Historical Remarks on Endurance Performance Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 470 2. Incremental Exercise Testing and the Interpretation of Blood Lactate Curves . . . . . . . . . . ....

The Virtual Physiology of Exercise Laboratory (VPEL) program was created to simulate the test design, data collection, and analysis phases of selected exercise physiology laboratories. The VPEL program consists of four modules: 1) cardiovascular, 2) maximal O(2) consumption (Vo(2max)), 3) lactate and ventilatory thresholds, and 4) respiratory exchange ratio. The purpose of this investigation wa...