Alvelolar hydatid disease is caused by E. multilocularis. Human infection occurs at the larval stage of this small tape worm (1.2 to 4.5 mm). In this article we studied alveolar hydatid disease in a 50 year old woman who presented with a hepatic mass. Liver biopsy and histopathologic evaluation showed alvelolar hydatidosis of the liver. Then resection of the left lobe of liver was done, with me...

Idiosyncratic liver injury occurs in a small fraction of people on certain drug regimens. The cause of idiosyncratic hepatotoxicity is not known; however, it has been proposed that environmental factors such as concurrent inflammation initiated by bacterial lipopolysaccharide (LPS) increase an individual's susceptibility to drug toxicity. Ranitidine (RAN), a histamine-2 receptor antagonist, cau...

Biliary cystadenoma is reported in an 8-year-old female Caucasian dog diagnosed by gross and microscopic examination. The lesion observed during postmortem examination on the liver was a 3×2cm cream-coloured raised nodule that extended into parenchyma another 2×4cm cyst filled with mucoid fluid. Histopathology showed multiloculated cysts lined columnar occasionally flattened epithelial cells, p...

in order to study the effect of garlic crude extract on growth rate and histopathology of liver, kidney and intestinal bulb, 120 fishes with initial mean weight of 95±22 g were divided to four groups. they were fed with 0, 10, 20 and 40 g/kg garlic crud extract in food for 1 month. at the end of experimental period, the growth rate was estimated and samples from liver, kidney and intestinal bul...

BACKGROUND Groundwater is believed to possess many beneficial effects due to its natural source of various minerals. In this study, we examined the effects of natural Jeju groundwater S1 (Samdasoo™), S2 and S3 pumped up from different locations of Jeju Island, Korea, along with local tap water, on body weight gain, serum lipids and lipoproteins, and liver histopathology in high-fat diet-induced...

BACKGROUND The inflammatory milieu in the liver as determined by histopathology is different in individual patients undergoing autologous islet cell transplantation. We hypothesized that inflammation related to fatty-liver adversely impacts islet survival. To test this hypothesis, we used a mouse model of fatty-liver to determine the outcome of syngeneic islet transplantation after chemical pan...

ABSTRACTDiazinon has a hepatotoxic effect since it is metabolized in the liver involving Kupffer cells (KCs) activation, increasing reactive oxygen species (ROS). The flavonoids contained shallot (Allium cepa L.) skin act as antioxidants neutralizing oxidative stress. This study aims to determine of ethanol extract (SSEE) on MDA level and activated KCs histopathology. total SSEE was measured us...

Background: Non-alcoholic steatohepatitis has been a well-known entity in association with Type 2 diabetes mellitus (DM) following insulin resistance and absence of overt hepatic manifestation. We aimed to study the histopathological features of liver in autopsy cases of known DM and identify the significant features and evaluate the extent of hepatic fibrosis seen in DM. Materials and Methods:...

Polycyclic aromatic hydrocarbons (PAHs) are priority contaminants in coastal and estuarine ecosystems under anthropogenic pressure. Although PAHs tend to accumulate the sediment, toxicity for benthic flat fish such as soles may be caused by released from sediment water column. Within this context, present investigation aims at recognizing toxicopathic effects elicited after waterborne exposure ...