malignant fibrous histiocytoma (mfh) is the most common soft tissue sarcoma of late adult life and may also arise as a primary tumor in bone. it is a rare condition that constitutes less than 1% of the malignant tumors of bone and commonly occurs in the mathaphysis of long bones of extremities such as the femur and tibia. the occurrence in the head and neck region is very rare. mfh of the jaws ...

Mature cystic teratoma (MCT) is the most common type of ovarian germ cell tumor occurring in females of reproductive age. It is typically benign, but rare malignant transformations have been reported in 1-2% of the cases. Among a wide variety of malignancies arising in MCTs, high grade lymphomas are the least common. We present a case of a 45- years -old female with a unilateral adnexal ma...

malignant peripheral nerve sheath tumor (mpnst), the principle malignancy of peripheral nerve origin, though rare in the general population, occurs with excessive frequency among patients with neurofi bromatosis. this tumor always arises in soft-tissues, usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. the pri...

patients with malignancy are at higher risk of thrombotic complications due to the hypercoagulability state. our objective in this study was to assess the serum concentrations of homocysteine, anti phospholipid antibodies, and anti cardiolipin in patients with benign and malignant breast tumors and study the effect of chemotherapy on the serum levels of these markers. a case control study was c...

Salivary  gland  tumors  accounts  for  less  than  1%  of  all  tumors.  Minor  salivary  gland  tumors (MSGTs) are uncommon and make up about 10% of all salivary gland neoplasms. The clinical and histopathological distribution of these tumors vary geographically. A case of a 38 yr old man with a minor salivary gland mass at chin region isreported here. The tumor invaded into the anterior ...

TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

Inflammatory myofibroblastic tumor is an uncommon benign neoplasm and its presentation in small bowel is rare. Due to clinical manifestation, laboratory data and radiologic results, there is an increased risk of over diagnosis as malignant tumors particularly malignant lymphoma in childhood therefore may be resulting in wrong therapeutic approach. However pathologic findings could be demonstrat...

Backgrounds: Evidence is accumulating to support disruption of tissue architecture as a powerful event in tumor formation. For the past four decades, intensive cancer research with the premise of “cancer as a cell based-disease” focused on finding oncogenes or tumor suppressor genes. However, the role of the tissue architecture was neglected. Three dimensional (3D) cell cultures which can recap...

SUMMARY Askin tumor is a peripheral neuroepithelioma originating in chest wall. It is a very aggressive tumor and with Ewing's sarcoma are the most frequent tumors of chest wall. The tumor is composed of small round or ovoid cells arranged in sheets with pseudorossette formation. Some times around vessels, glycogen staining is some times positive in H & E but always positive in E.M. In E.M be...