Chimaeric mice were obtained by injecting embryonic (CBA/H-T6 X PDE)F1 cells into PDE blastocysts. Three of 15 young were overt chimaeras. One female and one male chimaera survived to adulthood and after completion of test breeding, which demonstrated chimaerism in the germ cells of both, they were killed for study when aged 32 and 33 weeks respectively. Chromosome spreads were scored for the p...

Leukemic cells from nine cases of acute monocytic leukemia (AMoL) were characterized by multiple differentiation markers. Cells in most cases were phagocytic, carried an Fc receptor, and stained positively for alpha-naphthyl acetate esterase but negatively for naphthol AS-D chloroacetate esterase. However, subtle differences in marker expression were observed which suggested different degrees o...

In genetic studies, complex diseases are often analyzed searching for marker patterns that play a significant role in the susceptibility to the disease. In this paper we consider a dataset regarding periodontitis, that includes the analysis of nine genetic markers for 148 individuals. We analyze these data by using two APRIORI-based algorithms: APRIORISD and APRIORI with filtering. The discover...

Thromb Haemost 2008; 100: 9–10 Downey et al. published a paper in 1997 entitled ‘Novel and diagnostically applicable information from optical waveform analysis of blood coagulation in disseminated intravascular coagulation’ (1). Using a new automated coagulation analyzer, the MDA-180, the authors observed that during measurement of the aPTT, some samples became turbid immediately after addition...

Phylogenetic markers are widely used in DNA barcoding, DNA taxonomy, and amplicon based metagenomics. In this thesis, we address problems with phylogenetic marker analysis by developing novel models and algorithms. We present the Poisson Tree Processes (PTP) model for species delimitation using single-locus phylogenetic markers. We develop and test algorithms for maximum likelihood inference un...

This article considers receiver operating characteristic (ROC) analysis for bivariate marker measurements. The research interest is to extend tools and rules from univariate marker to bivariate marker setting for evaluating predictive accuracy of markers using a tree-based classification rule. Using an and-or classifier, an ROC function together with a weighted ROC function (WROC) and their con...

We consider the problem of locating instances of a known object in a novel scene by matching the fiducial features of the object. Our approach to the problem consists of two parts: a model for the appearance of the features and a model for the shape of the object. We then bind these parts together in a Bayesian framework and match the features sequentially, using the information about the locat...

We describe a new method for 2D fiducial tracking. We use region adjacency information together with angles between regions to encode IDs inside fiducials, whereas previous research by Kaltenbrunner and Bencina utilize region adjacency tree. Our method supports a wide ID range and is fast enough to accommodate real-time video. It is also very robust against false positive detection.