Intracerebroventricular (ICV) injection of streptozotocin (STZ) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic Alzheimer’s disease (SAD). Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) could delay or slow the clinical expression of SAD. Therefore, the benefi...

neurotoxicants present in water supply may affect human functions in terms of attention, response speed and perceptual motor speed. neurobehavioural performance can be influenced by gender, age and education levels. this study aims to assess the neurobehavioral performance of palm oil estate residents with private water supply in southern peninsular of malaysia.a total of 287 and 246 participan...

background: the cholinergic system plays an important role in learning and memory. administration of extracts of curcuma longa or its constituent, curcumin, have some roles in cognitive function in animals. the aim of the present study was to investigate the effects of curcumin in preventing spatial performance impairment induced by scopolamine, a cholinergic receptor antagonist, in rats using ...