BACKGROUND Migraine is a prevalent and debilitating disease that may, in part, arise because of disruption in neurovascular endothelia caused by elevated homocysteine. This study examined the homocysteine-lowering effects of vitamin supplementation on migraine disability, frequency and severity and whether MTHFRC677T genotype influenced treatment response. METHODS This was a randomized, doubl...

BACKGROUND Some researches have shown the association between iron deficiency and migraine headache in adults. The aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency. MATERIALS AND METHODS In a quasi- experimental study, monthly frequency, severity, duration and disability of headaches of ...

BACKGROUND AND METHODS Anthroposophic treatment for migraine is provided by physicians and includes special artistic and physical therapies and special medications. We conducted a prospective cohort study of 45 consecutive adult outpatients (89% women) starting anthroposophic treatment for migraine under routine conditions. Main outcomes were Average Migraine Severity (physician and patient rat...

Prophylactic migraine treatment has always been a challenge. Efficacy and tolerability are two main issues in current approved migraine prevention regimens. Since some migraineurs patients fail approved preventative agents, experts are always seeking newer agents. Memantine, a glutaminergic antagonist, could potentially be one of these agents. Objective of current study is assessing the efficac...

Prophylactic migraine treatment has always been a challenge. Efficacy and tolerability are two main issues in current approved migraine prevention regimens. Since some migraineurs patients fail approved preventative agents, experts are always seeking newer agents. Memantine, a glutaminergic antagonist, could potentially be one of these agents. Objective of current study is assessing the efficac...

Background and Objective: Migraine is a neurological syndrome that involves one-way or two-way recurrent headaches with a moderate to severe severity and lasts between 2 and 72 hours. Chronic migraines occur for about 3 months and at least 15 days or more per month, with a global incidence of 1.4 to 2.2 percent. The aim of this study was to compare the effectiveness of neurofeedback and transcr...

The International Classification of Headache Disorders lists several types of headaches [1]. Among primary headaches, migraine, tension-type headache and trigeminal autonomic cephalalgias are included. However, the distinction between migraine and tension-type headache, especially in children, is not always easy and the same subject can sometimes or periodically experience migraine and tension-...

Aim: In this study, we aimed to evaluate the relationship between anxiety, depression, and pain catastrophizing in individuals with without migraine. Method: Data of study was collected using socio-demographic data form, Beck Depression Scale (BDI), Anxiety (BAI), Pain Catastrophizing (PCS), Migraine Disability Assessment (MIDAS), Visual Analogue (VAS). Results: Of 183 patients, 80 were migrain...

The goals of acute treatment of migraine are cost-effective rapid relief, consistent reduction of disability, and reduced use of rescue medications. Key to acute treatment is matching medication to disability as a surrogate marker for disease severity with a stratified care approach. In the absence of vascular contraindications, triptans are first-line acute treatments for disabling migraine. A...

Introduction A growing body of literature has shown an association between somatic symptoms and insecure "attachment style." In a recent study, we found a relationship between migraine severity, ambivalent attachment style, and psychological symptoms in children/adolescents. There is evidence that caregivers' attachment styles and their way of management/expression of emotions can influence chi...