There is emerging evidence to show that high levels of NEFA contribute to endothelial dysfunction and impaired insulin sensitivity. However, the impact of NEFA composition remains unclear. A total of ten healthy men consumed test drinks containing 50 g of palm stearin (rich in SFA) or high-oleic sunflower oil (rich in MUFA) on separate occasions; a third day included no fat as a control. The fa...

Saturated (SFA) and monounsaturated (MUFA) fatty acids, the most abundant fatty acid species, have many divergent biological effects including the regulation of cell proliferation, programmed cell death and lipid-mediated cytotoxicity. Their distribution is regulated by Stearoyl-CoA Desaturases (SCD), the enzymes that convert SFA into MUFA. A positive correlation between high levels of tissue M...

OBJECTIVE Central obesity is associated with insulin resistance through factors that are not fully understood. We studied the effects of three different isocaloric diets on body fat distribution, insulin sensitivity, and peripheral adiponectin gene expression. RESEARCH DESIGN AND METHODS Eleven volunteers, offspring of obese type 2 diabetic patients with abdominal fat deposition, were studied...

INTRODUCTION Cardiovascular (CV) disease is a leading cause of global mortality. Despite clear evidence of the coexistence of several risk factors in young people as children and an understanding of the importance of the health behaviors in controlling CV disease, there are limited data on the relationships between risk factors and CV disease in young people. Therefore further study is required...

It is well documented that grain feeding stimulates adipogenesis in beef cattle, whereas pasture feeding depresses the development of adipose tissues, including intramuscular (i.m.) adipose tissue. Additionally, production practices that depress adipocyte differentiation also limit the synthesis of MUFA. Marbling scores and MUFA increase in parallel suggesting that stearoyl-coenzyme A desaturas...

This study was aimed to determine fatty acid compositions of Jerusalem artichoke herbages (Helianthus tuberosus) at five different phenological stages. harvested early vegetative, flowering, full and seed stages its herbage samples were obtained. In the herbages, saturated (∑SFA), unsaturated (∑UFA), polyunsaturated (∑PUFA), monounsaturated (MUFA), medium chain acids (∑MCFA), long (∑LCFA) very ...

OBJECTIVES To prospectively assess effects of select dietary fats on cognitive decline. DESIGN Prospective observational; 3-year follow-up. SETTING Northwestern University. PARTICIPANTS Four hundred eighty-two women aged 60 and older who participated in the Women's Health Initiative (WHI) Observational Study or in the control group of the WHI Diet Modification arm. MEASUREMENTS Dietary ...