نتایج جستجو برای: mycobacterium tuberculosis antigens
تعداد نتایج: 230037 فیلتر نتایج به سال:
Interferon-gamma release assays based on region of difference 1 antigens have improved diagnosis of latent tuberculosis infection (LTBI). However, these tests cannot discriminate between recently acquired infection (higher risk of progression to active tuberculosis) and remote LTBI. The objective of the present study was to evaluate the T-cell interferon-gamma responses to Mycobacterium tubercu...
introduction: tuberculosis (tb) caused by mycobacterium tuberculosis remains a major worldwide health problem. the only tb vaccine currently available is anattenuated strain of mycobacterium bovis termed bacillus calmette -guerin (bcg).the efficacy of bcg remains controversial. mycobacterium secretory proteins are generally considered important antigens for protection against tb. a major protei...
Abstract Background and Objective: A high level of homogeneity observed within all bacteria in the Mycobacterium tuberculosis complex makes a property that seriously challenges traditional biochemical-based identification methods of these pathogens in the laboratory. The work presented here was conducted to characterize Mycobacterium tuberculosis complex isolates in Golestan, Northern Iran. ...
The aim of our work here was to evaluate the immunogenicity of 60 mycobacterial antigens, some of which have not been previously assessed, notably a novel series of in vivo-expressed Mycobacterium tuberculosis (IVE-TB) antigens. We enrolled 505 subjects and separated them in individuals with and without latent tuberculosis infection (LTBI) vs. patients with active tuberculosis (TB). Following a...
Kwapinski, Jerzy B. (South African Institute for Medical Research, Johannesburg), and Marshall L. Snyder. Antigenic structure and serological relationships of Mycobacterium, Actinomyces, Streptococcus, and Diplococcus. J. Bacteriol. 82:632-639. 1961.-Chemical fractions, 72 in all, from four strains of Mycobacterium, four strains of Actinomyces, and four strains of Streptococceae, were tested in...
Mycobacterium tuberculosis readily activates both CD4 and Vd2 gd T cells. Despite similarity in function, these T-cell subsets differ in the antigens they recognize and the manners in which these antigens are presented by M. tuberculosis-infected monocytes. We investigated mechanisms of antigen processing of M. tuberculosis antigens to human CD4 and gd T cells by monocytes. Initial uptake of M....
Bovine brucellosis is caused by Brucella abortus. The bacterial pathogen causes economic losses because it induces abortion in cattle. Vaccination of calves with live B. abortus strain 19 a certain level protection but persistent antibodies against cell envelope lipopolysaccharide that make difficult to Distinguish Infected from Vaccinated Animals (DIVA). Live vaccine RB51 was developed elimina...
The production of interferon gamma (IFNgamma) guarantees effective T cell-mediated immunity against Mycobacterium tuberculosis infection. In the present study, we simply compare the in vitro immune responses to Mycobacterium antigens in terms of IFNg production in a total of 10 healthy Brazilian volunteers. Whole blood and mononuclear cells were cultivated in parallel with PPD, Ag85B, and M. bo...
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