نتایج جستجو برای: myelinated
تعداد نتایج: 3085 فیلتر نتایج به سال:
Myelinated pulmonary afferents are classified as rapidly adapting receptors (RARs) or slowly adapting receptors (SARs) by their adaptation rate. Behavior of SARs varies greatly, and therefore the present study tries to further categorize SARs according to their mechanical properties. Single-fiber activity of 104 SARs was examined in anesthetized, open-chest, artificially ventilated rabbits. Acc...
In the previous papers,TAKAHASHI et al.1,2)reported the effects of divalent transition metals,such as Co and Ni on the excitation mechanism of the myelinated nerve fibre.According to their observations,the main features of the effects of these metals are(a)increase in the rheobase,(b)enormous prolongation of the action current or potential forming a 'plateau' and (c) formation of a marked 'shou...
Sections of brain and spinal cord of mice and rats at 1, 3, 5, and 17 days after birth were examined with the electron microscope. In the early stages of myelinization only two to four lamellae surround the axon. These laminae are formed from the plasma membraces of glial processes, and in particular of oligodendroglial processes. In a later stage of myelinization a larger number of flattened g...
Cutaneous mechanosensory neurons detect mechanical stimuli that generate touch and pain sensation. Although opioids are generally associated only with the control of pain, here we report that the opioid system in fact broadly regulates cutaneous mechanosensation, including touch. This function is predominantly subserved by the delta opioid receptor (DOR), which is expressed by myelinated mechan...
Postherpetic neuralgia (PHN) is a common and exceptionally drug-resistant neuropathic pain condition. In this cross-sectional skin biopsy study, seeking information on the responsible pathophysiological mechanisms we assessed how ophthalmic PHN affects sensory and autonomic skin innervation. We took 2-mm supraorbital punch skin biopsies from the affected and unaffected sides in 10 patients with...
Autonomic function studies were performed on 15 patients with Friedreich's ataxia, and the results compared with those of 76 healthy subjects. There was an increase in resting supine heart rate, attributed to cardiac abnormalities. Other tests of sympathetic and parasympathetic function were normal. The normal autonomic function studies are consistent with the pathological findings of degenerat...
Currently accepted methods of tissue preparation for electron microscopy result in alterations of myelinated nerve fibers. In an attempt to minimize distortion of myelin, various fixation techniques, dehydration schedules, and embedding methods have been evaluated. It was found that the major damage to myelinated nerves occurs in the embedding procedure. A technique for embedding nerve tissue u...
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