Diversity-oriented synthesis of the biologically intriguing imidazo[1,2-a]pyridine-fused isoquinoline systems from readily available starting materials was achieved through the Groebke-Blackburn-Bienaymé reaction followed by a gold-catalyzed cyclization strategy. The synthetic approach is characterized by mild reaction conditions and a broad substrate scope, allowing for the rapid construction ...

Gemination aka twinning and fusion, are rare occurrences in posterior mandibular teeth, often requiring endodontic and surgical treatment for functional, orthodontic or cosmetic reasons. The diagnosis and design of a precise treatment plan in cases involving double teeth are in most cases challenging. The purpose of this case report is to describe a successful multidisciplinary treatment protoc...

background: since there has been no published report on the impact of permanent canines in shiraz population, this study was conducted to investigate the prevalence and the location of the impacted permanent canines in patients referred to the department of radiology of shiraz dental school in 2012. materials and methods: this was an analytic cross-sectional study on 1012 panoramic radiographs....

a case of a compound odontoma which caused delayed eruption of right maxillary central incisor in a ten year old girl is presented with clinical and radiographic findings. the patient presented with complaint of a hard painless swelling in the right anterior region of the maxilla and absence of right maxillary central incisor. after clinical examination, periapical and occlusal radiographs of t...

Riga’s papilloma or Cardarelli's apthae describes ulceration on the ventral of the tongue in neonates and infants. It is often associated with natal or neonatal teeth. It may rarely occur in older infants. Failure to diagnose and properly treat this lesion can result in inadequate nutrient intake for the infant. Treatment should begin conservatively and should focus on eliminating the source of...

The horn sharks (Heterodontidae: Chondrichthyes) represent one of four independent evolutions of durophagy in the cartilaginous fishes. We used high-resolution computed tomography (CT scanning) to visualize and quantify the mineralized tissue of an ontogenetic series of horn sharks. CT scanning of neonatal through adult California horn sharks (Heterodontus francisci) confirmed that this techniq...

An approach for introducing twists in pyrene-fused azaacenes is reported. Depending on the volume and the rigidity of the silyl groups, different-sized twist angles, which oscillate between 4° and 24°, are induced along the longitudinal conjugated backbone.

Bicyclo[2.2.2]octadiene-fused (BCOD-fused) bis(benzoborondipyrromethene)s (bisbenzoBODIPYs) bearing electron-withdrawing groups such as fluorine and cyano groups were prepared either by incorporating tetrafluoroisoindole moieties into BODIPY chromophores or by introducing cyano or ethoxycarbonyl groups at the 3,5-positions. The BCOD-fused bisbenzoBODIPYs were quantitatively converted to the cor...