Kushal Vesmaker and Sugato Banerjee Author informationArticle notesCopyright License information Department of Pharmacology Toxicology, National Institute Pharmaceutical Education Research, Kolkata, West Bengal, INDIA Corresponding author. *Correspondence: Dr. NIPER, Kolkata-700054, INDIA. Received: 29 July 2022; Revised: 28 September Accepted: 09 October 2022.

Neurodegenerative diseases, characterized by progressive loss of neurons, share common mechanisms such as apoptotic cell death, mitochondrial dysfunction, inflammation, and oxidative stress. Genus Boswellia is a genus in the Burseraceae family. It comprises several species traditionally used for treatment of chronic inflammatory diseases, cerebral edema, chronic pain syndrome, gastrointestinal d...

Molecular diagnostics provide a powerful method to detect and diagnose various neurological diseases such as Alzheimer's and Parkinson's disease. The confirmation of such diagnosis allows early detection and subsequent medical counseling that help specific patients to undergo clinically important drug trials. This provides a medical pathway to have better insight of neurogenesis and eventual cu...

This Society for Medicines Research symposium was held on June 6, 2007, at the Eli Lilly Research Centre in Windlesham, Surrey, United Kingdom. The meeting, organized by Eric Karran and Alan Palmer, reviewed the progress made, and the challenges still to be overcome, in discovering safe and effective therapies for the most common chronic neurodegenerative diseases: Alzheimer's disease, Parkinso...

Parkin is a unique, multifunctional ubiquitin ligase whose various roles in the cell, particularly in neurons, are widely thought to be protective. The pivotal role that Parkin plays in maintaining neuronal survival is underscored by our current recognition that Parkin dysfunction represents not only a predominant cause of familial parkinsonism but also a formal risk factor for the more common,...

Microglia are resident immune cells of the CNS. They are involved in the pathogenesis of diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, prion diseases as well as multiple sclerosis, amyotrophic lateral sclerosis and AIDS dementia complex. It is widely accepted that microglia contribute to the neurodegeneration through a release of a variety of proinflammato...

In the last twenty years, advanced magnetic resonance imaging (MRI) techniques have provided fundamental knowledge about neurodegenerative processes underlying several neu-rological and psychiatric diseases. The native approach in this field of study was the investigation of a single MRI parameter at a time: (a) blood oxygenation-level-dependent (BOLD) images, (b) anatomical 3D T1-weighted imag...