Cardiotoxicity is one of the challenges treating a cancer patient. With advancement treatment methods and production new drugs, life expectancy patients improved significantly.

‘‘IS THERE A TREATMENT?’’ are always the first words uttered when a parent or relative of a newly diagnosed child contacts National Tay-Sachs & Allied Diseases Association (NTSAD) upon hearing the devastating news that their loved one was diagnosed with one of the life-limiting diseases supported by NTSAD. The simple answer is always the same: ‘‘There are no treatments.’’ But first we try to in...

We increasingly recognize that erectile dysfunction (ED) usually arises from a mix of organic and psychogenic causes, yet management of this condition too often neglects the complexity of most cases of ED. While therapy with sildenafil and similar investigational drugs can play an important role in many cases of ED, physicians should recognize and try to address the psychological and interperso...

Decisions regarding investigational new drug applications for testing of all biologicals to be used in humans, including those designed to prevent or treat cancers, must be considered in terms of benefit/risk ratios. In order for a regulatory organization to make the appropriate decision regarding the testing of new biologicals in humans, it must have an extremely broad dialog within the critic...

In the context of television consumption and its opportunity costs the question arises how far experiencing mere representations of the outer world would have the same neural and cognitive consequences than actively interacting with that environment. Here we demonstrate that physical interaction and direct exposition are essential for the beneficial effects of environmental enrichment. In our e...

Medullary thyroid cancer (MTC) is a rare tumor arising from the calcitonin-producing parafollicular C cells of the thyroid gland, occurring either sporadically or alternatively in a hereditary form based on germline RET mutations in approximately one-third of cases. Historically, patients with advanced, metastasized MTC have had a poor prognosis, partly due to limited response to conventional c...