Periodontitis is a highly prevalent polymicrobial disease worldwide, yet the synergistic pattern of the multiple oral pathogens involved is still poorly characterized. Here, saliva, supragingival and subgingival plaque samples from periodontitis patients and periodontally healthy volunteers were collected and profiled with 16S rRNA gene pyrosequencing. Different oral habitats harbored significa...

Oral fluid analysis for herd monitoring is of interest to the commercial pig production in Korea. The aim of this study was to investigate pathogen-positive rates and correlations among eight pathogens associated with porcine respiratory disease complex by analyzing oral fluid samples from 214 pig groups from 56 commercial farms. Samples collected by a rope-chewing method underwent reverse-tran...

Objective: To evaluate the anticariogenic effect of dandelion extract against different oral pathogenic clinical isolates. Methods: In the present study, we evaluated the antimicrobial effect of dandelion against oral pathogens by the minimum inhibitory concentration and minimum bactericidal concentration. Clinical isolates such as Enterococcus faecalis, Streptococcus mutans, Streptococcus sali...

Oral infections caused by microorganisms have led to increased risk of oral health problems such as Dental Caries (DC), periodontitis and Oral Candidiasis (OC). Streptococcus mutans and Candida albicans are the primary organisms responsible for DC and OC, respectively. The goal of the presented study was to investigate the potential of probiotics to prevent and treat DC and OC. An in vitro assa...

INTRODUCTION Dental plaque biofilms are colonized by respiratory pathogens in mechanically-ventilated intensive care unit patients. Thus, improvements in oral hygiene in these patients may prevent ventilator-associated pneumonia. The goal of this study was to determine the minimum frequency (once or twice a day) for 0.12% chlorhexidine gluconate application necessary to reduce oral colonization...

Dysbiotic shifts in intestinal and pharyngeal microflora were studied in 22 normal volunteers in 9-, 14-, 105- and 520-d chamber experiments simulating some of the spaceflight factors. Two preparations were administered to prevent pharyngeal and intestinal dysbiosis: oral dry probiotic based on indigenous intestinal Enterococci and topical collagen-immobilized Lactobacterin based on indigenous ...