In the presence of nuisance parameters, we derive an explicit higher order asymptotic formula to compare the expected lengths of conndence intervals given by likelihood ratio statistics arising from the usual proole likelihood and various adjustments thereof. Highest posterior density regions, with approximate frequentist validity, are also included in the study.

For hypotheses of the type H0 : θ = θ0 vs H1 : θ 6= θ0 we demonstrate the equivalence of a Bayesian hypothesis test using a Bayes factor and the corresponding classical test, for a large class of models, which are detailed in the paper. In particular, we show that the role of the prior and critical region for the Bayes factor test is only to specify the type I error. This is their only role sin...

OBJECTIVES To qualitatively evaluate late dynamic contrast phases, 10, 20 and 30 min, after administration of Gd-EOB-DTPA with regard to biliary excretion in patients presenting with elevated liver enzymes without clinical signs of cirrhosis or hepatic decompensation and to compare the visual assessment of contrast agent excretion with histo-pathological fibrosis stage, contrast uptake paramete...

The acute and sub-acute toxicity of safranal were studied in rat and mice within 2 and 21 days after exposure, respectively. For subacute toxicity, changes in weight as well as biochemical, hematological and pathological parameters were studied. The intraperitoneal LD50 values of safranal were 1.48 mL/kg in male mice, 1.88 mL/kg in female mice and 1.50 mL/kg in male rats. Oral LD50 values were ...

In this paper, we introduce new voicing parameters to describe the speech signal and we study their effects on the classification of disordered voices. These parameters concern the fundamental frequency and the open quotient. The open quotient is defined as the ratio of the open phase by the pitch period. These parameters are calculated using the multiscale product method (MPM). The classificat...

quantitative analysis of the observed vocal fold dynamics in terms of symmetry and regularity is done with a time-dependent two-mass model of the vocal folds. The model's parameters are numerically optimized to emulate the observed non-stationary vocal fold vibrations. These parameters permit an objective interpretation of vocal fold oscillating asymmetries and allow a classification in normal ...