BACKGROUND Genome-wide expression data of gene microarrays can be used to infer gene networks. At a cellular level, a gene network provides a picture of the modules in which genes are densely connected, and of the hub genes, which are highly connected with other genes. A gene network is useful to identify the genes involved in the same pathway, in a protein complex or that are co-regulated. In ...

UNLABELLED With the rapid increase of omics data, correlation analysis has become an indispensable tool for inferring meaningful associations from a large number of observations. Pearson correlation coefficient (PCC) and its variants are widely used for such purposes. However, it remains challenging to test whether an observed association is reliable both statistically and biologically. We pres...

PURPOSE The level of the implant above the marginal bone and flap design have an effect on the bone resorption during the healing period. The aim of this study is to detect the relationship between the level of the implant at the implant placement and the bone level at the healing period in the mesial and distal side of implants placed with flapless (FL) and full-thickness flap (FT) methods. ...

this study aims to determine the relationship between organizational culture factors and employees’ group dynamics in general office of education in mazandaran province during 2013-2014. it is a descriptive-survey research. the statistical population consists of 273 employees working in general office of education in mazandaran province by whom 120 people are selected by stratified random sampl...

Methods Sixty-one asymptomatic children (31 girls, 30 boys) aged 7-9 years (mean 7.9 ±0.8) were assessed once by one observer for the sagittal curvatures of the trunk: thoracic kyphosis (TK), lumbar lordosis (LL) and sacral slope (SS) first with digital photography and with Rippstein plurimeter. Statistical analysis was performed using paired Student t-test, Wilcoxon matched-pairs and Pearson c...

Pearson product-moment correlation coefficients are a wellpracticed quantification of linear dependence seen across many fields. When calculating a sample-based correlation coefficient, the accuracy of the estimation is dependent on the quality and quantity of the sample. Like all statistical models, these correlation coefficients can suffer from overfitting, which results in the representation...

many other biomedical journals dealing with cancer research, often publishes papers whose principal aim it is to test the association between quantative measurements of biological variables. When these are expressed on continuous scales, the statistics most frequently adopted to test their association are the Bravais-Pearson (parametric) and the Spearman (non-parametric) correlation coefficient...

One of the famous controversies in statistics is the dispute between Fisher and Neyman-Pearson about the proper way to conduct a test. Hubbard and Bayarri (2003) gave an excellent account of the issues involved in the controversy. Another famous controversy is between Fisher and almost all Bayesians. Fisher (1956) discussed one side of these controversies. Berger’s Fisher lecture attempted to c...

We tested the hypothesis that the proportion of normal results in tests ordered by a physician correlates directly with the proportion of tests that are disapproved by a utilization review audit for inappropriate test use. Auditors reviewed 3497 charts for 13 067 repeated determinations of 10 diagnostic tests ordered by 81 medical residents to determine if test use had been appropriate, accordi...