BACKGROUND Metabolic Syndrome (MS) is prevalant in China, especially according to the pediatric obesity group. Based on the MS-CHN2012 definition for Chinese children and adolescents the need to explore and establish a convienent MS screening become imminent. This study aims to investigate the optimal cut-off values, compare the accuracy for the (TriGlycerides (TG) to High-Density Lipoprotein C...

Berry, MPH, MS, RD, CSP, lead nutritionist, Pediatric Feeding Disorders Program, Marcus Autism Center, Atlanta, GA; Patricia Novak, MPH, RD, EMPOWER project coordinator, Children’s Hospital of Los Angeles, Los Angeles, CA; Nicole Withrow, PhD, RD, assistant professor and dietetic internship coordinator, University of Northern Colorado, Greeley; Brianne Schmidt, RD, clinical nutrition specialist...

OBJECTIVE To determine the health care costs associated with pediatric multiple sclerosis (MS). METHODS We performed a retrospective analysis of all patients with MS 18 years of age or younger who were diagnosed or treated between 2002 and 2012 in a population-based cohort. Demographics and health care costs were extracted from the Intermountain Healthcare Enterprise Data Warehouse. Patients ...

122. Clinical and Microbiologic Characteristics of Pediatric Patients with Lemierre Syndrome Andrew Nuibe, MD; Elizabeth Doby, MD; Adam L. Hersh, MD, PhD; Chris Stockmann, MSc; E. Kent Korgenski, MS; Andrew Pavia, MD, FIDSA, FSHEA; Jeffrey M. Bender, MD; Kwabena Ampofo, MD; Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah School of Medicine, Salt Lake City...

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Introduction Magnesium sulphate (MS), causes bronchodilation by inhibiting bronchial smooth muscle contraction, interferes with parasympathetic stimulation, and prevents acetylcholine release to axon terminals [1]. It reduces inflammation by inhibiting mast cell degranulation and reduces thromboxane, histamine and leukotrienes [2]. Some pediatric studies suggest that MS, b-2-agonists and steroi...

Rafael de Liz Pocztaruk1* Luis Carlos da Fontoura Frasca2* Elken Gomes Rivaldo3* Paulo Roberto Castro Mattia4* Rafael Araújo Vidal1* Eduardo Fernandes3* Maria Beatriz Duarte Gavião5 1DDS, MS, Assistant Professor 2DDS, MS, PhD Professor, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil 3 DDS, MS, PhD 4 DDS, MS 5 DDS, MS PhD, Professor, Department of Pediatric Dentistry, Piracica...

OBJECTIVE The aim of this study was to examine the relative contributions of body mass index (BMI) and pubertal measures for risk and age of onset of pediatric MS. METHODS Case-control study of 254 (63% female) MS cases (onset<18 years of age) and 420 (49% female) controls conducted at 14 U.S. Pediatric MS Centers. Sex- and age-stratified BMI percentiles were calculated using CDC growth chart...

BACKGROUND Leptin and adipocyte-fatty acid binding protein (A-FABP) are produced by white adipose tissue and may play a role in chronic inflammation in Multiple Sclerosis (MS). To assess leptin and A-FABP in relapsing and progressive forms of MS. METHODS Adipokine levels were measured in untreated adult relapsing-remitting MS (RRMS), secondary progressive MS (SPMS), primary progressive MS (PP...

BACKGROUND Natalizumab, a humanized monoclonal antibody raised against alpha4 integrins, is approved for treatment of active relapsing-remitting multiple sclerosis (RRMS) in adult patients. OBJECTIVE To determine the safety, effectiveness, and tolerability of natalizumab use in pediatric patients with MS. DESIGN Case report. SETTING Center for MS in childhood and adolescents, Göttingen, G...